Dougherty Lab has a new preprint

The Dougherty Lab has a new preprint, “TRAP-based allelic translation efficiency imbalance analysis to identify genetic regulation of ribosome occupancy in specific cell types in vivo.” The work was done in collaboration with the Lawson Lab. Yating Liu, a...

Wang Lab publishes new paper in Science Advances

The Wang Lab recently published a new paper in Science Advances, “Cellular diversity of the regenerating caudal fin.” Yiran Hou, a graduate student in the lab, is first author on the paper. Ting Wang, Professor of Genetics, Professor of Computer Science...

Wang Lab has new preprint on transposable elements

The Wang Lab has a new preprint, “Transcript assembly improves expression quantification of transposable elements in single cell RNA-seq data.” Wanqing Shao, a postdoc in the lab, is first author on the preprint. Ting Wang, PhD, Professor of Genetics,...

Mitra Lab publishes paper in Cell

The Mitra Lab recently published a paper in Cell, “Self-Reporting Transposons Enable Simultaneous Readout of Gene Expression and Transcription Factor Binding in Single Cell.” Arnav Moudgil, a graduate student in the Mitra Lab, is first author on the paper....

Wang Lab and Dougherty Lab publish paper in Science Advances

The Wang Lab and Dougherty Lab published a paper recently in Science Advances, “DeepH&M: Estimating single-CpG hydroxymethylation and methylation levels from enrichment and restriction enzyme sequencing methods.” Yu He, a former graduate student in the...

Former Dougherty Lab grad student lead author on new preprint

Chengran Yang, a former graduate student in the Dougherty Lab, is lead author on a new preprint, “Genomic and multi-tissue proteomic integration for understanding the biology of disease and other complex traits.” Congratulations, Chengran!

Dougherty Lab publishes paper in Biological Psychiatry

The Dougherty Lab recently published a paper in Biological Psychiatry, “Massively Parallel Reporter Assays: Defining Functional Psychiatric Genetic Variants across Biological Contexts.” Bernie Mulvey, a graduate student in the lab, is first author. Tomás...

Dougherty Lab publishes new paper in Human Molecular Genetics

The Dougherty Lab published a paper in Human Molecular Genetics, “Functions of Gtf2i and Gtf2ird1 in the developing brain: transcription, DNA binding and long-term behavioral consequences.” Nathan Kopp, a former graduate student in the lab, and Kayla...

Dutcher Lab publishes paper in collaboration with MRC

The Dutcher Lab has published a paper in collaboration with researchers at the MRC Laboratory of Molecular Biology, Cambridge. The paper, “CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions,” appears in a recent issue of Structure. Takashi...

Graduate student joins Turner and Dutcher Labs

Zach Payne, a graduate student in the Molecular Genetics and Genomics program at Washington University School of Medicine, will be a joint student in the Turner and Dutcher Labs to look at cilia and autism. Welcome, Zach!

Two graduate students join the Mitra Lab

Pam Recio and Lori Llaci have joined the Mitra Lab as graduate students.  Pam received a Bachelor of Science in Molecular Biology from California State University Monterey Bay. Her undergraduate research involved assessing the role that specific genes-LAC1 and LAG1-...

Mitra Lab graduate student has new preprint

Arnav Moudgil, a graduate student in the Mitra Lab, has a new preprint, “The qBED track: a novel genome browser visualization for point processes.” Moudgil is a first author and Ting Wang, PhD, the Sanford and Karen Loewentheil Distinguished Professor of...

Cohen Lab graduate student gets F31 Fellowship

Ryan Friedman, a graduate student in the Cohen Lab, recently got an F31 Fellowship from the National Human Genome Research Institute to continue his work applying active machine learning and synthetic biology to better understand non-coding sequences. Congratulations,...

Dutcher Lab publishes new paper in Nature

The Dutcher Lab has a new paper published in Nature, “Mapping and characterization of structural variation in 17,795 human genomes.” Haley J Abel, PhD, Instructor in Genetics at Washington University School of Medicine, is first author on the paper. Susan...

Milbrandt Lab has paper published in Nature Communications

The Milbrandt Lab recently had a paper published in Nature Communications, “Peripheral nerve resident macrophages share tissue-specific programming and features of activated microglia.” Peter Wang and Aldrin K. Y. Yim, graduate students in the lab, are...

Lawson Lab publishes paper in Physiological Genomics

The Lawson Lab recently published a paper in Physiological Genomics, “Genetic background and diet affect brown adipose gene co-expression networks associated with metabolic phenotypes.” Caryn Carson, a graduate student in the lab, is first author on the...

Dougherty Lab publishes new paper in Brain and Behavior

The Dougherty Lab published a new paper in Brain and Behavior, “The trajectory of gait development in mice.” Shyam Akula, a former undergraduate researcher in the lab, is first author on the paper. Joe Dougherty, PhD, Associate Professor of Genetics at...

Dougherty Lab publishes paper in Human Molecular Genetics

The Dougherty Lab recently had a paper published in Human Molecular Genetics, “Functions of Gtf2i and Gtf2ird1 in the developing brain: transcription, DNA-binding, and long term behavioral consequences.” Nathan Kopp, PhD, a former graduate student in the...

Dougherty Lab undergrad awarded BioSURF fellowship

Jelani Deajon-Jackson, an undergraduate student in the Dougherty Lab, was recently awarded a BioSURF fellowship by Washington University in St. Louis to train with his mentor Mike Vasek, a postdoc in the lab. The Washington University Biology Summer Undergraduate...

Dougherty and Mitra Labs publish paper in PNAS

The Dougherty and Mitra Labs had a paper published in PNAS, “A viral toolkit for recording transcription factor–DNA interactions in live mouse tissues.” Alex Cammack, a graduate student in the Miller Lab who recently defended, is first author on the paper....

Tips for Graduate Students During Shelter in Place

By Jim Skeath, PhD, Professor of Genetics at Washington University School of Medicine I’ve always felt that the keys to success in graduate school are to work hard and have fun – to work hard, think hard, do experiments, and to enjoy what you do and where you do it. I...

Dougherty Lab has new preprint

The Dougherty Lab has a new preprint, “Activity-dependent translation in astrocytes.” Darshan Sapkota, a postdoc in the lab, is first author on the preprint. Joe Dougherty, PhD, Associate Professor in the Department of Genetics at Washington University...

Milbrandt Lab publishes paper in PNAS

The Milbrandt Lab has a new paper in PNAS, “Cell-autonomous expression of the acid hydrolase galactocerebrosidase.” The paper is in collaboration with the Sands Lab and the Bruno Benitez, PhD, Assistant Professor in Psychiatry at Washington University...

Skeath Lab publishes paper in eLife

The Skeath Lab recently had a paper published in eLife, “Unc-4 acts to promote neuronal identity and development of the take-off circuit in the Drosophila CNS.” Haluk Lacin, PhD, a member of the lab, is first author on the paper, and Jim Skeath, Professor...

Morris Lab graduate student awarded fellowship in NSF GRFP

Christy Hoffmann, a graduate student in the Morris Lab, was recently awarded a fellowship the National Science Foundation Graduate Research Fellowship Program. The program “recognizes and supports outstanding graduate students in NSF-supported science,...

Sheng Chih (Peter) Jin awarded NIH grant

Sheng Chih (Peter) Jin, PhD, Assistant Professor in the Department of Genetics at Washington University School of Medicine, was recently awarded an NIH grant for his project, “Integrative Genomic Analysis of Congenital Heart Disease.” Congratulations, Dr....

Wang Lab publishes new paper in Nature

The Wang Lab recently had a paper published in Nature, “A genomic and epigenomic atlas of prostate cancer in Asian populations.” Hyung Joo Lee, a postdoc in the lab, is a first author on the paper. Ting Wang, Professor of Genetics, Professor of Computer...

Dougherty Lab publishes a new paper in Scientific Reports

The Dougherty Lab recently had a paper published in Scientific Reports, “CNS microRNA profiles: a database for cell type enriched microRNA expression across the mouse central nervous system.” Yating Liu, a programmer in the lab, is an author on the paper,...

Wang Lab works with WashU Med team to tackle COVID-19

Washington University School of Medicine researchers are tackling the coronavirus pandemic, and Ting Wang, the Sanford and Karen Loewentheil Distinguished Professor of Medicine, and his lab are getting in on the effort. The lab built a genome browser to help...

Cohen Lab publishes paper in eLife

The Cohen Lab recently had a paper published in eLife, “Synthetic and genomic regulatory elements reveal aspects of cis-regulatory grammar in mouse embryonic stem cells.” Dana King, PhD, previously a graduate student in the Cohen Lab, is first author on...

Mitra Lab has new paper published in Nucleic Acids Research

The Mitra Lab has a new paper published in Nucleic Acids Research, “Quantitative analysis of transcription factor binding and expression using calling cards reporter arrays.” Jiayue Liu, a graduate student in the lab, is first author on the paper....

Dougherty Lab publishes new paper in Neural Development

The Dougherty Lab has a new paper in Neural Development, “An inducible Cre mouse line to sparsely target nervous system cells, including Remak Schwann cells.” Darshan Sapkota, a postdoc in the lab, is first author on the paper. Joe Dougherty, PhD,...

Samantha Morris joins Development as associate editor

Samantha Morris, PhD, Assistant Professor of Genetics and Developmental Biology at Washington University in St. Louis, and Allen Distinguished Investigator, recently joined Development as an associate editor. Morris’s appointment comes as the journal responds to...

Milbrandt Lab has new paper published in Experimental Neurology

The Milbrant Lab has a new paper published in Experimental Neurology, “cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons.” Yo Sasaki, PhD, Associate Professor in the Department of Genetics at...

Morris Lab has two new preprints

The Morris Lab has two new preprints: The first, “Capybara: A computational tool to measure cell identity and fate transitions,” includes first author Wenjun Kong, a graduate student in the lab; Yuheng Fu, an undergraduate student in the lab; and Samantha...

Dougherty Lab welcomes new members

The Dougherty Lab recently welcomed new members including Rachael, a senior graduate student who will be working with Kayla Nygaard, a graduate student in the lab; Chayla, a first year PhD rotation student working with Bernie Mulvey, a graduate student in the lab;...

Wang Lab has paper published in eLife

The Wang Lab had a paper published recently in eLife, “Derivation of trophoblast stem cells from naïve human pluripotent stem cells.” Authors include Xiaoyun Xing, a staff scientist in the Wang Lab; Ting Wang, PhD, Professor of Genetics, Professor of...

Samantha Morris named 2020 Sloan Research Fellow

Samantha Morris, Assistant Professor of Genetics and Developmental Biology at Washington University School of Medicine, was named a 2020 Sloan Research Fellow. The fellowship honors scholars in the U.S. and Canada “whose creativity, leadership, and independent...

Wang Lab has new preprint on coronavirus epidemic

The Wang Lab has a new preprint, “Exploring the coronavirus epidemic using the new WashU Virus Genome Browser.” The preprint focuses on the new WashU Virus Genome Browser, a web-based portal for viewing virus genomic data. The browser houses 16 complete...

Wang Lab releases new WashU Virus Genome Browser

The Wang Lab has released a new WashU Virus Genome Browser. “In addition to several included data tracks, the browser supports user-uploaded sequences, as well as two visualization platforms: a genomic track view and a phylogenetic tree view,” the lab said...

Tychele Turner wins 2019 Human Genetics SMRT Grant

Tychele Turner, PhD, Assistant Professor of Genetics at Washington University School of Medicine, recently won the 2019 Human Genetics SMRT Grant from Pacific Biosciences. Congratulations, Dr. Turner! Read more about Dr. Turner and her work in this Q&A with...

Susan Dutcher publishes two reviews

Susan Dutcher, Ph.D., Professor in the Department of Genetics at Washington University, has published two reviews, one on the structure of cytoplasmic dynein and the other on Hydin, a protein in the central pair microtubules. “Dynein tails: how to hitch a ride...

Dutcher Lab publishes three papers in latter half of 2019

The Dutcher Lab published three noteworthy papers in the latter half of 2019. The first paper, “De Novo Mutations in FOXJ1 Result in a Motile Ciliopathy with Hydrocephalus and Randomization of Left/Right Body Asymmetry,” appears in the American Journal of...

Wang Lab graduate student has paper published in Genome Biology

Mayank Choudhary, a graduate student in the Wang Lab, had a paper published recently in Genome Biology. The paper, “Co-opted transposons help perpetuate conserved higher-order chromosomal structures,” shows that transposable elements heavily contribute to...

Morris Lab has new preprint with Solnica-Krezel Lab

The Morris Lab has a new preprint with the Solnica-Krezel Lab, “High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human embryonic stem cell gastruloid cultures.” Read more about the preprint and the authors...

Wang Lab publishes paper in Nature Communications

The Wang Lab published a paper recently in Nature Communications, “The epigenomic landscape of transposable elements across normal human development and anatomy.” Erica Pehrsson, a postdoc in the Wang Lab, is first author on the paper. Mayank Choudhary and...

Dougherty Lab publishes paper in Human Molecular Genetics

The Dougherty Lab had a paper published recently in Human Molecular Genetics. The paper, “Gtf2i and Gtf2ird1 mutation do not account for the full phenotypic effect of the Williams syndrome critical region in mouse models,” thoroughly defines a set of...

Province and Long Life Family Study get $68M NIH grant

The Province Lab and the Long Life Family study got a $68 million NIH grant to investigate what contributes to extreme longevity.  Michael A. Province, Ph.D., professor of genetics at Washington University School of Medicine, is the principal investigator on the...

Milbrandt Lab publishes paper in Glia

The Milbrandt Lab published a paper recently in Glia. The paper, “Disrupting insulin signaling in Schwann cells impairs myelination and induces a sensory neuropathy,” shows that Schwann cells may play an important role in diabetic neuropathy and targeting...

Milbrandt Lab publishes paper in Molecular Neurobiology

The Milbrandt Lab had a paper published recently in Molecular Neurobiology. The paper, “DLK Activation Synergizes with Mitochondrial Dysfunction to Downregulate Axon Survival Factors and Promote SARM1-Dependent Axon Degeneration,” was published in...

Gary Stormo receives 2019 Faculty Achievement Award

Gary Stormo, Ph.D., Joseph Erlanger Professor in the Department of Genetics and the Center for Genome Sciences and Systems Biology at Washington University School of Medicine, recently was honored with the Carl and Gerty Cori Faculty Achievement Award. Dr. Stormo,...

Samantha Morris named Allen Distinguished Investigator

Samantha A. Morris, Ph.D., Assistant Professor of Developmental Biology and Genetics at Washington University School of Medicine in St. Louis, was recently named an Allen Distinguished Investigator by The Paul G. Allen Frontiers Group of the Allen Institute. Morris,...

Schedl Lab has new preprint on GLP-1 Notch signaling

The Schedl Lab has a new preprint, “GLP-1 Notch – LAG-1 CSL control of the germline stem cell fate is mediated by transcriptional targets lst-1 and sygl-1.” Jian Chen, a postdoctoral researcher in the lab, is first author on the preprint. Tim Schedl,...

Jeff Milbrandt honored as distinguished faculty at Founders Day

Jeff Milbrandt, M.D., Ph.D., the James S. McDonnell Professor of Genetics and head of the Department of Genetics at Washington University School of Medicine in St. Louis, was recently honored with a Distinguished Faculty Award at Washington University’s annual...

Morris Lab publishes paper in CMGH

The Morris Lab, in collaboration with the Warner Lab at Washington University School of Medicine in St. Louis, recently published a paper in CMGH. The paper, “Single-Cell Analysis Reveals Regional Reprogramming During Adaptation to Massive Small Bowel Resection...

Genetics graduate students win awards at MGG/CSB/HSG Annual Retreat

Graduate students in the Department of Genetics at Washington University School of Medicine won awards at the recent MGG/CSB/HSG annual retreat. Clarice Hong from the Cohen Lab, Robert Chen from the Gordon Lab, and Celine St. Pierre from the Lawson Lab won “Best...

Dougherty Lab presents at Society for Neuroscience annual meeting

The Dougherty Lab recently presented at the annual Society for Neuroscience meeting in Chicago. Dr. Susan Maloney, Instructor in Psychiatry and a member of the Dougherty Lab, presented on modeling social motivation in the mouse and the role of Shank3B and the oxytocin...

Dutcher Lab has new preprint on Primary ciliary dyskinesia

The Dutcher Lab has a new preprint, “Mutation of CFAP57 causes primary ciliary dyskinesia by disrupting the asymmetric targeting of a subset of ciliary inner dynein arms.” Mathieu Bottier, a postdoc in the Dutcher Lab, and Mihaela Stoyanova, a technician...

Reshma Bhagat joins Dougherty Lab as postdoc

Reshma Bhagat has joined the Dougherty Lab as a postdoc. Dr. Bhagat comes from a background studying molecular perturbations in neural cell types elicited by Zika virus components. Check out Dr. Bhagat’s work here.

Jeff Milbrandt senior author on new SARM1 paper in JCI Insight

Jeffrey Milbrandt, M.D., Ph.D., the James S. McDonnell Professor of Genetics and head of the Department of Genetics at Washington University School of Medicine, is a senior author on a new paper from the DiAntonio Lab recently published in JCI Insight. The paper,...