COURSE OBJECTIVES

Bio5491 – Advanced Genetics provides an overview of basic concepts and techniques in genetics and their use in answering fundamental questions in biology. The lectures focus primarily on studies carried out in yeast, C. elegans, Drosophila, mouse, and humans to illustrate the power of genetics as an experimental tool.

COURSE FORMAT

  • 2 lectures per week and 1 additional group meeting
    • Class meets Tuesday and Thursday from1:30-3:00 pm (ends 3:15 pm some days, see schedule)
      • Holden Auditorium (in FLTC) for T/Th lectures
      • First day of class is January 16th
      • Last day of class is April 30th
    • Additional meetings are either discussion sections (Monday) or Special Topics lectures (Monday or Wednesday)
      • Special Topics Lectures with TAs:
        • Genetics Review- Wednesday 1/17 4:00 pm (Zoom)
        • Proposal Topic Brainstorming Session- Monday 2/12 12:00 NOON (Room TBA)
        • Y2H/Genetic Screens Review- Monday 2/19 12:00 NOON (Room TBA)
        • Special Topics Lecture- Monday 3/18 12:00 NOON (Room TBA)
      • Discussion section
        • Time and Place: Mondays 12:00 – 1:00 or other TBD
        • The section will either involve a small group discussion on a specific paper in separate rooms or be a special topic lecture. (Previously a note here said “Remote via Zoom” but that was left over from a prior year; meetings will mostly be in person, locations TBD.)
        • Similar to those for MCB and Nucleic Acids or a Special Topics Lecture.
        • For your small group discussion placement, see Discussion Group tab; you will also be contacted by your faculty group leader before the first small group meeting
  • Please email both TAs any questions on homework or course material for assistance.
  • Major Project
    • Write an NIH-style postdoctoral fellowship proposal.
    • Topic due February 28th.
    • Abstracts and Specific Aims due March 18th.
    • Complete proposal due by 12:00 NOON on Monday, April 29th.
    • Study Sections will be held on May 6, 7, & 8 from 1:00-4:00 pm.
      • Rooms TBA
      • Each student is required to attend their one assigned study section.
      • Each student will be given two proposals for their Study Section and is required to read and provide a written and oral critique of both proposals at the Study Section.

SCHEDULE

  • To see the course schedule and access documents, please click on the Spring 2024 tab in the upper right corner of this site.
    • If you have difficulty accessing any links or find errors, please contact Doris Wu at shanyun@wustl.edu or Ena Haseljic at e.haseljic@wustl.edu
  • Please refer to updated schedules for problem set due dates. (Spring 2024 tab)