Services

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The Genome Engineering Center is a core facility offering a variety of custom genome editing services.

 

Custom and Validated TALEN or CRISPR Vectors

The GEC designs, assembles, and validates transcription activator-like effector nucleases (TALENs), and clustered regularly spaced palindromic repeats (CRISPR) vectors for each user-defined modification.  We validate activity of each endonuclease in a cell line from the species of interest for targets in the human, mouse, or rat genome.

Custom Knockout Cell Lines

The GEC will work with investigators to create targeted knockout cell lines.

Custom Knockin Cell Lines

The GEC will work with investigators to create targeted knockin cell lines.  These modifications include, but are not limited to, point mutations, codon modifications, targeted insertions or deletions, and gene tagging.

 

Ready to Get Started?

Please fill out our Custom Cell Line form, Custom Nuclease form, or Contact Us.