Postdoctoral Fellow: Undiagnosed Disease Network screening and analysis

Objective: Employ C. elegans to identify and study the function of genes that cause rare disorders in humans, as a component of the NIH Undiagnosed Disease Network (UDN).  As part of a team effort with other researchers and clinicians, candidate disease gene-variants are identified, knocked into the worm ortholog by Cas9/CRISPR and phenotype assessed.  The development of a follow-up independent research program from one or more of the cases is possible.  The project is performed under the guidance of Tim Schedl & Stephen Pak, co-directors of the Washington University School of Medicine Undiagnosed Disease Network Worm Model Organism Screening Center. See <https://undiagnosed.hms.harvard.edu/research/model-organisms-phase-ii/>

Applicants must have completed PhD, MD or foreign equivalent.  Experience in C. elegans, genetics, molecular, cellular, developmental or neuro-biology is advantageous, but not required.  The desired candidate is a team player with a strong work ethic.  International scientists and US citizens are equally eligible for these fully funded positions.

Washington University is a premier medical research institution, highly collaborative with strengths in model organism basic science and clinical research.  St Louis is a diverse multi-cultural environment that is friendly, very affordable and has easy access to numerous indoor and outdoor activities.

For more information or to apply, email Tim Schedl < ts@wustl.edu >.  To apply, send cover letter, a CV and contacting formation for three letters of reference.