Buchser Lab has a new preprint

The Buchser Lab has a new preprint, “Mitochondrial Phenotypes Distinguish Pathogenic MFN2 Mutations by Pooled Functional Genomics Screen.” Lead authors include Alex Yenkin, a research technician in the lab, and Jack Bramley, a staff scientist in the lab....

Milbrandt Lab publishes paper in eLife

The Milbrandt and DiAntonio Labs have a new paper in eLife, “SARM1 depletion rescues NMNAT1 dependent photoreceptor cell death and retinal degeneration.” Yo Sasaki, PhD, Associate Professor in the Department of Genetics at Washington University School of...

Biotech from Jeff Milbrandt and team acquired by Eli Lilly

Eli Lilly & Company recently acquired Disarm Therapeutics, a pre-clinical NAD-boosting company treating neuropathy and neurodegenerative diseases, for $135 million and a potential additional $1.2 billion in milestones. Disarm was founded by Atlas Venture; Jeff...

Milbrandt Lab has paper published in Nature Communications

The Milbrandt Lab recently had a paper published in Nature Communications, “Peripheral nerve resident macrophages share tissue-specific programming and features of activated microglia.” Peter Wang and Aldrin K. Y. Yim, graduate students in the lab, are...

Milbrandt Lab publishes paper in Glia

The Milbrandt Lab published a paper recently in Glia. The paper, “Disrupting insulin signaling in Schwann cells impairs myelination and induces a sensory neuropathy,” shows that Schwann cells may play an important role in diabetic neuropathy and targeting...

Milbrandt Lab publishes paper in Molecular Neurobiology

The Milbrandt Lab had a paper published recently in Molecular Neurobiology. The paper, “DLK Activation Synergizes with Mitochondrial Dysfunction to Downregulate Axon Survival Factors and Promote SARM1-Dependent Axon Degeneration,” was published in...

Jeff Milbrandt honored as distinguished faculty at Founders Day

Jeff Milbrandt, M.D., Ph.D., the James S. McDonnell Professor of Genetics and head of the Department of Genetics at Washington University School of Medicine in St. Louis, was recently honored with a Distinguished Faculty Award at Washington University’s annual...

Jeff Milbrandt senior author on new SARM1 paper in JCI Insight

Jeffrey Milbrandt, M.D., Ph.D., the James S. McDonnell Professor of Genetics and head of the Department of Genetics at Washington University School of Medicine, is a senior author on a new paper from the DiAntonio Lab recently published in JCI Insight. The paper,...

Milbrandt lab publishes paper on Schwann cell O-GlcNAcylation

The Milbrandt lab published a paper recently on Schwann cell O-GlcNAcylation. The paper, “Schwann cell O-GlcNAcylation promotes peripheral nerve remyelination via attenuation of the AP-1 transcription factor JUN,” appears in PNAS. Sungsu Kim, Ph.D., an...