Be sure to check out these recently published articles: Congrats to Kelsey Krus (DiAntonio/Milbrandt labs) on her paper demonstrating that loss of STMN2 in mice induces slowly progressive motor deficits, a cardinal feature of ALS. Exciting work from the DiAntonio...
March 4, 2022: Congratulations to Caitlin Dingwall and the Milbrandt/DiAntonio labs on their new preprint, “Macrophage depletion blocks congenital SARMI-dependent neuropathy”.
The Milbrandt Lab collaborated on a paper with the Wu Lab from Harvard Medical School and the DiAntonio Lab at Washington University School of Medicine, “Multiple domain interfaces mediate SARM1 autoinhibition.” Chen Shen, a postdoc in the Wu Lab, is lead...
The Milbrandt and DiAntonio Labs have a new paper in eLife, “SARM1 depletion rescues NMNAT1 dependent photoreceptor cell death and retinal degeneration.” Yo Sasaki, PhD, Associate Professor in the Department of Genetics at Washington University School of...
The Mitra and Milbrandt Labs had a paper published recently in Genome Research, “High-throughput single-cell functional elucidation of neurodevelopmental disease–associated genes reveals convergent mechanisms altering neuronal differentiation.” Matt Lalli,...
Matt Lalli, a postdoc in the Mitra and Milbrandt Labs, recently accepted a position as Instructor in the Department of Psychiatry, Division of Seaver Autism Center for Research and Treatment, at Icahn School of Medicine at Mount Sinai. Congratulations, Matt! Best of...
The DiAntonio and Milbrandt Labs published a paper in the Journal of Cell Biology, “SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration.” Kwang Woo Ko, a postdoc in the DiAntonio Lab, is lead author on the...
The Buchser, DiAntonio, and Milbrandt Labs have published a paper in Scientific Data, “Domain-centric database to uncover structure of minimally characterized viral genomes.” Jack Bramley, a lead scientist in the Buchser Lab, is lead author on the paper. ...
The Milbrandt Lab recently had a paper published in Nature Communications, “Peripheral nerve resident macrophages share tissue-specific programming and features of activated microglia.” Peter Wang and Aldrin K. Y. Yim, graduate students in the lab, are...
The Milbrandt Lab and the Mitra Lab and scientists at the McDonnell Genome Institute have a new preprint, “Rapid and extraction-free detection of SARS-CoV-2 from saliva with colorimetric LAMP.” Matt Lalli, a postdoc in the Milbrandt and Mitra Labs, is a...
The Milbrandt and DiAntonio Labs have a new preprint, “SARM1 depletion rescues NMNAT1 dependent photoreceptor cell death and retinal degeneration.” Yo Sasaki, PhD, Associate Professor in the Department of Genetics at Washington University School of...
The Milbrandt Lab has a new paper in PNAS, “Cell-autonomous expression of the acid hydrolase galactocerebrosidase.” The paper is in collaboration with the Sands Lab and the Bruno Benitez, PhD, Assistant Professor in Psychiatry at Washington University...
The Milbrandt Lab has a new preprint, “Peripheral nerve resident macrophages are microglia-like cells with tissue-specific programming.” Peter Wang, a postdoc in the lab, is first author on the preprint. Aldrin Yim, a graduate student in the lab, is also...
The Milbrandt Lab published a paper recently in Glia. The paper, “Disrupting insulin signaling in Schwann cells impairs myelination and induces a sensory neuropathy,” shows that Schwann cells may play an important role in diabetic neuropathy and targeting...
The Milbrandt Lab had a paper published recently in Molecular Neurobiology. The paper, “DLK Activation Synergizes with Mitochondrial Dysfunction to Downregulate Axon Survival Factors and Promote SARM1-Dependent Axon Degeneration,” was published in...
The Milbrandt and DiAntonio Labs published a paper recently in Science, “TIR domains of plant immune receptors are NAD+-cleaving enzymes that promote cell death.” Kow Essuman, Ph.D., a graduate student in the Milbrandt Lab, is a lead author on the paper....
Kow Essuman, a graduate student in the Milbrandt Lab, recently defended his thesis recently at Washington University School of Medicine in St. Louis. Kow’s talk, “The Enzymatic Function of the TIR domain: From Axon Degeneration to Innate Immunity,”...
Kow Essuman, a graduate student in the Milbrandt Lab, and Alex Russo, a graduate student in the DiAntonio Lab, are finalists for the O’Leary Prize. As finalists, Kow and Alex will give short presentations of their research at the O’Leary Prize Competition on...
The Milbrandt and DiAntonio labs had a paper published recently on gene therapy that blocks peripheral damage in mice. The paper, “Gene therapy targeting SARM1 blocks pathological axon degeneration in mice,” appears in a recent issue of the Journal of...
Denis Avey, Ph.D., a postdoc in the Mitra and Milbrandt labs, had a paper accepted recently by Cell Reports. The paper, “Single cell RNAseq uncovers a robust transcriptional response to morphine by glia,” looks at the morphine-dependent transcriptional...
The Milbrandt lab published a paper recently on Schwann cell O-GlcNAcylation. The paper, “Schwann cell O-GlcNAcylation promotes peripheral nerve remyelination via attenuation of the AP-1 transcription factor JUN,” appears in PNAS. Sungsu Kim, Ph.D., an...
