Schedl Lab

Washington University Genetics

GLD-1 mediated translational repression of RME-2 results in yolk uptake only in large oocytes – Photo

Spatial restriction of RME-2 accumulation by GLD-1 mediated translational repression allows yolk up-take only in large oocytes

Gonad Arms dissected from wild-type adult hermaphrodite are stained with DAPI to visualize DNA (upper panel as blue), anti-GLD-1 (lower panel as green), anti-RME-2 (lower panel as red), and anti-yolk Ab (lower panel as blue). GLD-1 and RME-2 accumulation is mutually exclusive and yolk is accumulated only in the 3-4 most proximal oocytes.

  • Tim Schedl, Ph.D
    Department of Genetics
    Campus Box #8232
    Washington University School of Medicine
    4566 Scott Ave.
    St. Louis, MO 63110


    PHONE: (314)362-6164 [lab]
    FAX: (314)362-7855