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Connor Auditorium (FLTC)

October 2022

Emma Farley, PhD
Assistant Professor
Department of Medicine
University of California-San Diego

October 13 @ 12:00 pm - 1:00 pm

presents, "Affinity optimizing enhancer variants disrupt development" Hosted by: Dr. Barak Cohen In-person only:  Connor Auditorium (FLTC) Talk abstract:  An emerging regulatory principle governing enhancers is the use of suboptimal affinity binding sites to encode tissue-specific gene expression during development. Here we discover that affinity optimizing single-nucleotide variants can violate this principle, disrupt tissue-specific gene expression, and alter phenotypes in Ciona, mice, and humans.

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Barbara Cheifet, PhD
Senior Editor
Nature Biotechnology
Springer Nature

October 20 @ 12:00 pm - 1:00 pm

presents, "Publishing for impact" Hosted by: Dr. Ting Wang In-person only:  Connor Auditorium (FLTC) Talk abstract:  In this talk, I will share tips on the publishing process, what journals look for, and how to productively interact with editors. I will also look forward to answering any questions related to academic publishing.

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Laurence Pelletier, PhD
Principal Investigator & Cancer Cell Biologist
Lunenfeld-Tanenbaum Research Institute, Toronto

October 27 @ 12:00 pm - 1:00 pm

presents, "Protein interaction profiling of centrosomes in normal and disease states" Hosted by:  Dr. Susan Dutcher In-person only:  Connor Auditorium (FLTC)

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November 2022

Kun Zhang, PhD
Professor
Department of Bioengineering
University of California, San Diego

November 10 @ 12:00 pm - 1:00 pm

presents, "A multi-omics cell atlas for human healthy and disease kidney" Hosted by:  Dr. Shamim Mollah In-person only:  Connor Auditorium (FLTC) Talk abstract:  Detailed characterization of the cell types comprising the highly complex human organs is essential to understanding their functions. Such tasks require highly scalable experimental approaches to examine multiple aspects of the molecular state of individual cells, registering cells to 3D coordinates, as well as the computational integration to produce unified cell state annotations and interpretation with biological…

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Samantha Morris, PhD
Associate Professor
Departments of Genetics and Developmental Biology
Washington University School of Medicine

November 17 @ 12:00 pm - 1:00 pm

presents, "What are my cells? A journey into cell identity and new genomic technologies" Hosted by: Dr. Joe Dougherty In-person only:  Connor Auditorium (FLTC) Talk abstract:  A mechanistic understanding of how cell identity is established and maintained is fundamental to the precise engineering of cell fate. Here, I will present new genomic technologies developed by my lab to permit single-cell lineage tracing throughout reprogramming, accompanied by recording of TF-binding and chromatin accessibility profiling. Integrating this information using our unique computational tools for interrogating gene regulatory networks…

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December 2022

Hui Shen, PhD
Associate Professor
Department of Epigenetics
Van Andel Institute

December 1 @ 12:00 pm - 1:00 pm

presents, "Epigenetics’: Lesson Learned from Ovarian Cancer and the Female Reproductive Tract " Hosted by:  Dr. Ting Wang In-person only:  Connor Auditorium (FLTC)

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Student-invited speaker
Stephen Johnson Memorial Lecture
Jessica Tollkuhn, PhD
Associate Professor
Cold Spring Harbor Laboratory

December 8 @ 12:00 pm - 1:00 pm

presents, "Hormonal regulation of gene expression defines sex-variable biology" Hosted by:  Simona Sarafinovska and Genetics trainees & postdocs In-person only:  Connor Auditorium (FLTC)

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Jeffrey Miner, PhD
E & J Slatopolsky Professor of Medicine in Nephrology
Division of Nephrology
Department of Medicine
Washington University School of Medicine

December 15 @ 12:00 pm - 1:00 pm

presents, "Genetic manipulation of the kidney’s filtration barrier: insights into Alport syndrome" Hosted by:  Dr. Tychele Turner In-person only:  Connor Auditorium (FLTC)

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January 2023

Erik Musiek, MD, PhD
Charlotte & Paul Hagemann Professor
Department of Neurology
Washington University School of Medicine

January 5, 2023 @ 12:00 pm - 1:00 pm

presents, "Regulation of glial cell gene expression and function by the circadian clock" Hosted by:  Dr. Tristan Li In-person only:  Connor Auditorium (FLTC)

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Francesca Luca, PhD
Professor
Center for Molecular Medicine and Genetics
Wayne State University School of Medicine

January 12, 2023 @ 12:00 pm - 1:00 pm

presents, "Genetic, developmental and social factors in immune cell gene expression and asthma" Hosted by:  Dr. Barak Cohen In-person only:  Connor Auditorium (FLTC)

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Karen Miga, PhD
Assistant Professor
Department of Biomolecular Engineering
University of California, Santa Cruz

January 19, 2023 @ 12:00 pm - 1:00 pm

presents, "Discovering new biology and function in complete, telomere-to-telomere (T2T) genomes" Hosted by:  Dr. Ting Wang In-person only:  Connor Auditorium (FLTC)

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Marian Walhout, PhD
Professor & Chair
Department of Systems Biology
University of Massachusetts Chan Medical School

January 26, 2023 @ 12:00 pm - 1:00 pm

presents, "Worms, bugs & drugs" Hosted by:  Dr. Tychele Turner In-person only:  Connor Auditorium (FLTC)

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February 2023

Nenad Sestan, MD, PhD
Harvey and Kate Cushing Professor of Neuroscience
Professor of Comparative Medicine, Genetics, & Psychiatry
Department of Neuroscience
Yale University School of Medicine

February 2, 2023 @ 12:00 pm - 1:00 pm

presents, "Building the Human Cortex: Development and Evolution of Neural Circuits Underlying Cognitive Control" Hosted by:  Dr. Peter Jin In-person only:  Connor Auditorium (FLTC)

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Susan Strome, PhD
Distinguished Professor of Molecular, Cell, & Developmental Biology
Department of Molecular, Cell, & Developmental Biology
University of California-Santa Cruz

February 9, 2023 @ 12:00 pm - 1:00 pm

presents, "Inherited chromatin states shape transcription patterns in offspring and grandoffspring" Hosted by: Drs. Susan Dutcher and Tim Schedl In-person only:  Connor Auditorium (FLTC)

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Kristen Kroll, PhD
Professor
Department of Developmental Biology
Washington University School of Medicine

February 16, 2023 @ 12:00 pm - 1:00 pm

presents, "Epigenetic regulation of human cortical development and its disruption to cause neurodevelopmental disorders" Hosted by:  Dr. Tristan Li In-person only:  Connor Auditorium (FLTC)

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Xuehua Zhong, PhD
Professor
Department of Biology
Washington University

February 23, 2023 @ 12:00 pm - 1:00 pm

presents, "Epigenetic regulation and environmental adaptation" Hosted by:  Dr. Ting Wang In-person only:  Connor Auditorium (FLTC)

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March 2023

Marius Wernig, MD, PhD
Professor of Pathology & Co-Director
Institute for Stem Cell Biology and Regenerative Medicine
Stanford University

March 2, 2023 @ 12:00 pm - 1:00 pm

presents, "Cellular reprogramming to study neuronal lineage specification and develop cell therapies for the brain" Hosted by:  Dr. Joe Dougherty In-person only:  Connor Auditorium (FLTC)

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Chad Pearson, PhD
Associate Professor
Department of Cell & Developmental Biology
University of Colorado Anschutz Medical Campus

March 9, 2023 @ 12:00 pm - 1:00 pm

presents, "Negative impacts of chromosome 21 gene dosage on primary cilia formation and signaling" Hosted by:  Dr. Susan Dutcher In-person only:  Connor Auditorium (FLTC)

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Ann Morning, PhD
Professor
Department of Sociology
New York University

March 16, 2023 @ 12:00 pm - 1:00 pm

presents, "Title TBD" Hosted by:  Dr. Brett Maricque In-person only:  Connor Auditorium (FLTC)

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Student-invited speaker
Melissa Boneta Davis, PhD
Associate Professor of Development & Cell Biology
Department of Surgery
Weill Cornell Medicine

March 23, 2023 @ 12:00 pm - 1:00 pm

presents, "Role of African Ancestry in genomic and proteomic changes in breast cancer disparities" Hosted by:  Alla Karpova and Genetics trainees & postdocs In-person only:  Connor Auditorium (FLTC)

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Bruce Gelb, MD
Professor & Dean for Child Health Research
Gogel Family Chair & Director of The Mindich Child Health & Development Institute
Director of the Center for Molecular Cardiology
Departments of Pediatrics and Genetics & Genomic Sciences
Icahn School of Medicine @ Mount Sinai

March 30, 2023 @ 12:00 pm - 1:00 pm

presents, "The RASopathies: Too much, too little and getting to just right" Hosted by:  Dr. Peter Jin In-person only:  Connor Auditorium (FLTC)

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April 2023

Karen Oegema, PhD
Professor
Department of Cellular & Molecular Medicine
University of California, San Diego School of Medicine

April 6, 2023 @ 12:00 pm - 1:00 pm

presents, "Mitotic centrosomes: assembly & functions" Hosted by:  Dr. Susan Dutched In-person only:  Connor Auditorium (FLTC)

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Jennifer Wang, PhD
Assistant Professor
Department of Biology
Washington University in St. Louis

April 13, 2023 @ 12:00 pm - 1:00 pm

presents, "Fitting the pieces together: how cells make centrosomes and cilia" Hosted by:  Dr. Tychele Turner In-person only:  Connor Auditorium (FLTC)

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Ali Mortazavi, PhD
Professor
Department of Developmental and Cell Biology
University of California, Irvine

April 20, 2023 @ 12:00 pm - 1:00 pm

presents, "Title TBD" Hosted by:  Dr. Heather Lawson In-person only:  Connor Auditorium (FLTC)

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Ellen Hoffman, MD, PhD
Assistant Professor
Yale Child Study Center & Yale Neurogenetics Program
Yale University School of Medicine

April 27, 2023 @ 12:00 pm - 1:00 pm

presents, "Functional analysis of autism risk genes in zebrafish" Hosted by:  Dr. Joe Dougherty In-person only:  Connor Auditorium (FLTC)

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May 2023

Jesse Engreitz, PhD
Assistant Professor
Department of Genetics
Stanford University

May 4, 2023 @ 12:00 pm - 1:00 pm

presents, "Mapping the regulatory wiring of the genome to connect disease variants to functions" Hosted by:  Dr. Heather Lawson In-person only:  Connor Auditorium (FLTC)

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Lacra Bintu, PhD
Assistant Professor of Bioengineering
Department of Bioengineering
Stanford University

May 11, 2023 @ 12:00 pm - 1:00 pm

presents, "The sequence determinants of human transcriptional activators and repressors: high-throughput discovery and systematic perturbations" Hosted by:  Dr. Barak Cohen In-person only:  Connor Auditorium (FLTC)

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Kristopher Kahle, MD, PhD
Associate Professor & Director, Pediatric Neurosurgery
Department of Neurosurgery
Harvard Medical School and Massachusetts General Hospital

May 18, 2023 @ 12:00 pm - 1:00 pm

presents, "Genomics of developmental brain anomalies" Hosted by:  Dr. Peter Jin In-person only:  Connor Auditorium (FLTC)

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Ben Major, PhD
Alan A. and Edith L. Wolff Professor of Cell Biology and Physiology
Departments of Cell Biology & Physiology and Otolaryngology
Washington University School of Medicine

May 25, 2023 @ 12:00 pm - 1:00 pm

presents, "Protein-protein proximity networks reveal therapeutic vulnerabilities in cancer" Hosted by:  Dr. Tychele Turner In-person only:  Connor Auditorium (FLTC)

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