Loading Events

← Back to Events

Connor Auditorium (FLTC)

February 2023

Susan Strome, PhD
Distinguished Professor of Molecular, Cell, & Developmental Biology
Department of Molecular, Cell, & Developmental Biology
University of California-Santa Cruz

February 9 @ 12:00 pm - 1:00 pm

presents, "Inherited chromatin states shape transcription patterns in offspring and grandoffspring" Talk abstract:  The role that chromatin states serve in transmitting gene expression information across generations via sperm and oocytes is not well understood. We utilized a model in which C. elegans sperm and oocyte alleles were inherited in different states of the repressive mark H3K27me3. This resulted in the alleles achieving different transcriptional states within the nuclei of offspring. Using this model, we showed that sperm alleles inherited without H3K27me3 were sensitive to up-regulation in offspring…

Find out more »

Kristen Kroll, PhD
Professor
Department of Developmental Biology
Washington University School of Medicine

February 16 @ 12:00 pm - 1:00 pm

presents, "Epigenetic regulation of human cortical development and its disruption to cause neurodevelopmental disorders" Talk abstract: Work in my laboratory focuses on modeling gene regulatory networks that control various aspects of human brain development. We are interested in identifying novel transcriptional and epigenetic regulators of these networks, defining mechanisms by which they control brain development, and studying how pathogenic mutations in genes encoding these regulators contribute to neurodevelopmental disorders. Hosted by:  Dr. Tristan Li In-person only:  Connor Auditorium (FLTC)

Find out more »

MGI Seminar Series
Willie Buchser, PhD
Associate Professor
Department of Genetics
McDonnell Genome Institute
Washington University School of Medicine

February 22 @ 12:00 pm - 1:00 pm

presents, "Deep Cellular Phenotyping, the newest tools for Omics or Screening" In-person only:  Connor Auditorium (FLTC)

Find out more »

Xuehua Zhong, PhD
Professor
Department of Biology
Washington University

February 23 @ 12:00 pm - 1:00 pm

presents, "Epigenetic regulation and environmental adaptation" Talk abstract:  The Zhong laboratory is interested in how cellular machines sense intrinsic and extrinsic cues and alter chromatin landscapes to generate adaptive responses. They focus on epigenetic regulation by exploring how chromatin dynamics is established, maintained, erased, and inherited over time, and how altered chromatin modifications lead to improved plant traits and environmental adaptation. They combine functional genomics and high-throughput proteomics and genomics techniques together with genetic and biochemical tools to understand the function…

Find out more »

March 2023

Marius Wernig, MD, PhD
Professor of Pathology & Co-Director
Institute for Stem Cell Biology and Regenerative Medicine
Stanford University

March 2 @ 12:00 pm - 1:00 pm

presents, "Cellular reprogramming to study neuronal lineage specification and develop cell therapies for the brain" Talk title: I will talk about neuronal cell specification centered around transcription factor regulation and applications of microglia replacement therapies. Hosted by:  Dr. Joe Dougherty In-person only:  Connor Auditorium (FLTC)

Find out more »

Chad Pearson, PhD
Associate Professor
Department of Cell & Developmental Biology
University of Colorado Anschutz Medical Campus

March 9 @ 12:00 pm - 1:00 pm

presents, "Negative impacts of chromosome 21 gene dosage on primary cilia formation and signaling" Talk abstract:  Trisomy 21, the genetic cause of Down syndrome, disrupts primary cilia formation and function, in part through elevated Pericentrin, a centrosome protein encoded on chromosome 21. Our work reveals that elevated Pericentrin from trisomy 21 disrupts multiple early steps of ciliogenesis and creates persistent trafficking defects in ciliated cells and in a mouse model of Down syndrome. Hosted by:  Dr. Susan Dutcher In-person only: …

Find out more »

Ann Morning, PhD
Professor
Department of Sociology
New York University

March 16 @ 12:00 pm - 1:00 pm

presents, "Title TBD" Hosted by:  Dr. Brett Maricque In-person only:  Connor Auditorium (FLTC)

Find out more »

Student-invited speaker
Melissa Boneta Davis, PhD
Associate Professor of Development & Cell Biology
Department of Surgery
Weill Cornell Medicine

March 23 @ 12:00 pm - 1:00 pm

presents, "Role of African Ancestry in genomic and proteomic changes in breast cancer disparities" Hosted by:  Alla Karpova and Genetics trainees & postdocs In-person only:  Connor Auditorium (FLTC)

Find out more »

Bruce Gelb, MD
Professor & Dean for Child Health Research
Gogel Family Chair & Director of The Mindich Child Health & Development Institute
Director of the Center for Molecular Cardiology
Departments of Pediatrics and Genetics & Genomic Sciences
Icahn School of Medicine @ Mount Sinai

March 30 @ 12:00 pm - 1:00 pm

presents, "The RASopathies: Too much, too little and getting to just right" Talk abstract:  Noonan syndrome and the related disorders, now called the RASopathies, are phenotypically related traits arising from perturbations, largely engendering gain of function, in the RAS/mitogen-activated protein kinase signal transduction pathway. In this lecture, insights gained from phenotype-first and genotype-first studies of the RAsopathies will be provided as well as those from cell and animal model research, informing the development of mechanistic therapies for these genetic traits.…

Find out more »

April 2023

Karen Oegema, PhD
Professor
Department of Cellular & Molecular Medicine
University of California, San Diego School of Medicine

April 6 @ 12:00 pm - 1:00 pm

presents, "Mitotic centrosomes: assembly & functions" Hosted by:  Dr. Susan Dutched In-person only:  Connor Auditorium (FLTC)

Find out more »

Jennifer Wang, PhD
Assistant Professor
Department of Biology
Washington University in St. Louis

April 13 @ 12:00 pm - 1:00 pm

presents, "Fitting the pieces together: how cells make centrosomes and cilia" Hosted by:  Dr. Tychele Turner In-person only:  Connor Auditorium (FLTC)

Find out more »

Ali Mortazavi, PhD
Professor
Department of Developmental and Cell Biology
University of California, Irvine

April 20 @ 12:00 pm - 1:00 pm

presents, "Title TBD" Hosted by:  Dr. Heather Lawson In-person only:  Connor Auditorium (FLTC)

Find out more »

Ellen Hoffman, MD, PhD
Assistant Professor
Yale Child Study Center & Yale Neurogenetics Program
Yale University School of Medicine

April 27 @ 12:00 pm - 1:00 pm

presents, "Functional analysis of autism risk genes in zebrafish" Hosted by:  Dr. Joe Dougherty In-person only:  Connor Auditorium (FLTC)

Find out more »

May 2023

Jesse Engreitz, PhD
Assistant Professor
Department of Genetics
Stanford University

May 4 @ 12:00 pm - 1:00 pm

presents, "Mapping the regulatory wiring of the genome to connect disease variants to functions" Hosted by:  Dr. Heather Lawson In-person only:  Connor Auditorium (FLTC)

Find out more »

Lacra Bintu, PhD
Assistant Professor of Bioengineering
Department of Bioengineering
Stanford University

May 11 @ 12:00 pm - 1:00 pm

presents, "The sequence determinants of human transcriptional activators and repressors: high-throughput discovery and systematic perturbations" Hosted by:  Dr. Barak Cohen In-person only:  Connor Auditorium (FLTC)

Find out more »

Kristopher Kahle, MD, PhD
Associate Professor & Director, Pediatric Neurosurgery
Department of Neurosurgery
Harvard Medical School and Massachusetts General Hospital

May 18 @ 12:00 pm - 1:00 pm

presents, "Genomics of developmental brain anomalies" Hosted by:  Dr. Peter Jin In-person only:  Connor Auditorium (FLTC)

Find out more »

MGI Seminar Series

Rich Head, MS
Professor, Department of Genetics
Director, Genome Technology Access Center @ McDonnell Genome Institute (MTAC@MGI)
Washington University School of Medicine and

Robert Fulton, MS
Assistant Professor, Department of Genetics
McDonnell Genome Institute
Washington University School of Medicine

May 24 @ 12:00 pm - 1:00 pm

presents, “Title TBD” In-person only:  Connor Auditorium (FLTC)

Find out more »

Ben Major, PhD
Alan A. and Edith L. Wolff Professor of Cell Biology and Physiology
Departments of Cell Biology & Physiology and Otolaryngology
Washington University School of Medicine

May 25 @ 12:00 pm - 1:00 pm

presents, "Protein-protein proximity networks reveal therapeutic vulnerabilities in cancer" Hosted by:  Dr. Tychele Turner In-person only:  Connor Auditorium (FLTC)

Find out more »

June 2023

Student-invited speaker
Stephen Johnson Memorial Lecture
Jessica Tollkuhn, PhD
Associate Professor
Cold Spring Harbor Laboratory

June 1 @ 12:00 pm - 1:00 pm

presents, "Hormonal regulation of gene expression defines sex-variable biology" Talk abstract:  My lab studies how nuclear hormone receptors modulate gene expression in the brain at single-cell resolution, and how this affects development of and activity within circuits that mediate specific behaviors. We anticipate that the hormone-regulated genes we have identified will contribute to established sex differences in the incidence and etiology of neurological and psychiatric disorders. Hosted by:  Simona Sarafinovska, Din Selmanovic, and Genetics trainees & postdocs In-person only:  Connor…

Find out more »
+ Export Events