October 2022
Emma Farley, PhD
Assistant Professor
Department of Medicine
University of California-San Diego
presents, "Affinity optimizing enhancer variants disrupt development" Hosted by: Dr. Barak Cohen In-person only: Connor Auditorium (FLTC) Talk abstract: An emerging regulatory principle governing enhancers is the use of suboptimal affinity binding sites to encode tissue-specific gene expression during development. Here we discover that affinity optimizing single-nucleotide variants can violate this principle, disrupt tissue-specific gene expression, and alter phenotypes in Ciona, mice, and humans.
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Barbara Cheifet, PhD
Senior Editor
Nature Biotechnology
Springer Nature
presents, "Publishing for impact" Hosted by: Dr. Ting Wang In-person only: Connor Auditorium (FLTC) Talk abstract: In this talk, I will share tips on the publishing process, what journals look for, and how to productively interact with editors. I will also look forward to answering any questions related to academic publishing.
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Laurence Pelletier, PhD
Principal Investigator & Cancer Cell Biologist
Lunenfeld-Tanenbaum Research Institute, Toronto
presents, "Protein interaction profiling of centrosomes in normal and disease states" Hosted by: Dr. Susan Dutcher In-person only: Connor Auditorium (FLTC)
Find out more »November 2022
Kun Zhang, PhD
Professor
Department of Bioengineering
University of California, San Diego
presents, "A multi-omics cell atlas for human healthy and disease kidney" Hosted by: Dr. Shamim Mollah In-person only: Connor Auditorium (FLTC) Talk abstract: Detailed characterization of the cell types comprising the highly complex human organs is essential to understanding their functions. Such tasks require highly scalable experimental approaches to examine multiple aspects of the molecular state of individual cells, registering cells to 3D coordinates, as well as the computational integration to produce unified cell state annotations and interpretation with biological…
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Samantha Morris, PhD
Associate Professor
Departments of Genetics and Developmental Biology
Washington University School of Medicine
presents, "What are my cells? A journey into cell identity and new genomic technologies" Hosted by: Dr. Joe Dougherty In-person only: Connor Auditorium (FLTC) Talk abstract: A mechanistic understanding of how cell identity is established and maintained is fundamental to the precise engineering of cell fate. Here, I will present new genomic technologies developed by my lab to permit single-cell lineage tracing throughout reprogramming, accompanied by recording of TF-binding and chromatin accessibility profiling. Integrating this information using our unique computational tools for interrogating gene regulatory networks…
Find out more »December 2022
Hui Shen, PhD
Associate Professor
Department of Epigenetics
Van Andel Institute
presents, "Epigenetics’: Lesson Learned from Ovarian Cancer and the Female Reproductive Tract " Hosted by: Dr. Ting Wang In-person only: Connor Auditorium (FLTC)
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Student-invited speaker
Stephen Johnson Memorial Lecture
Jessica Tollkuhn, PhD
Associate Professor
Cold Spring Harbor Laboratory
presents, "Hormonal regulation of gene expression defines sex-variable biology" Hosted by: Simona Sarafinovska and Genetics trainees & postdocs In-person only: Connor Auditorium (FLTC)
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Jeffrey Miner, PhD
E & J Slatopolsky Professor of Medicine in Nephrology
Division of Nephrology
Department of Medicine
Washington University School of Medicine
presents, "Genetic manipulation of the kidney’s filtration barrier: insights into Alport syndrome" Hosted by: Dr. Tychele Turner In-person only: Connor Auditorium (FLTC)
Find out more »January 2023
Erik Musiek, MD, PhD
Charlotte & Paul Hagemann Professor
Department of Neurology
Washington University School of Medicine
presents, "Regulation of glial cell gene expression and function by the circadian clock" Hosted by: Dr. Tristan Li In-person only: Connor Auditorium (FLTC)
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Francesca Luca, PhD
Professor
Center for Molecular Medicine and Genetics
Wayne State University School of Medicine
presents, "Genetic, developmental and social factors in immune cell gene expression and asthma" Hosted by: Dr. Barak Cohen In-person only: Connor Auditorium (FLTC)
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Karen Miga, PhD
Assistant Professor
Department of Biomolecular Engineering
University of California, Santa Cruz
presents, "Discovering new biology and function in complete, telomere-to-telomere (T2T) genomes" Hosted by: Dr. Ting Wang In-person only: Connor Auditorium (FLTC)
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Marian Walhout, PhD
Professor & Chair
Department of Systems Biology
University of Massachusetts Chan Medical School
presents, "Worms, bugs & drugs" Hosted by: Dr. Tychele Turner In-person only: Connor Auditorium (FLTC)
Find out more »February 2023
Nenad Sestan, MD, PhD
Harvey and Kate Cushing Professor of Neuroscience
Professor of Comparative Medicine, Genetics, & Psychiatry
Department of Neuroscience
Yale University School of Medicine
presents, "Building the Human Cortex: Development and Evolution of Neural Circuits Underlying Cognitive Control" Hosted by: Dr. Peter Jin In-person only: Connor Auditorium (FLTC)
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Susan Strome, PhD
Distinguished Professor of Molecular, Cell, & Developmental Biology
Department of Molecular, Cell, & Developmental Biology
University of California-Santa Cruz
presents, "Inherited chromatin states shape transcription patterns in offspring and grandoffspring" Hosted by: Drs. Susan Dutcher and Tim Schedl In-person only: Connor Auditorium (FLTC)
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Kristen Kroll, PhD
Professor
Department of Developmental Biology
Washington University School of Medicine
presents, "Epigenetic regulation of human cortical development and its disruption to cause neurodevelopmental disorders" Hosted by: Dr. Tristan Li In-person only: Connor Auditorium (FLTC)
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Xuehua Zhong, PhD
Professor
Department of Biology
Washington University
presents, "Epigenetic regulation and environmental adaptation" Hosted by: Dr. Ting Wang In-person only: Connor Auditorium (FLTC)
Find out more »March 2023
Marius Wernig, MD, PhD
Professor of Pathology & Co-Director
Institute for Stem Cell Biology and Regenerative Medicine
Stanford University
presents, "Cellular reprogramming to study neuronal lineage specification and develop cell therapies for the brain" Hosted by: Dr. Joe Dougherty In-person only: Connor Auditorium (FLTC)
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Chad Pearson, PhD
Associate Professor
Department of Cell & Developmental Biology
University of Colorado Anschutz Medical Campus
presents, "Negative impacts of chromosome 21 gene dosage on primary cilia formation and signaling" Hosted by: Dr. Susan Dutcher In-person only: Connor Auditorium (FLTC)
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Ann Morning, PhD
Professor
Department of Sociology
New York University
presents, "Title TBD" Hosted by: Dr. Brett Maricque In-person only: Connor Auditorium (FLTC)
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Student-invited speaker
Melissa Boneta Davis, PhD
Associate Professor of Development & Cell Biology
Department of Surgery
Weill Cornell Medicine
presents, "Role of African Ancestry in genomic and proteomic changes in breast cancer disparities" Hosted by: Alla Karpova and Genetics trainees & postdocs In-person only: Connor Auditorium (FLTC)
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Bruce Gelb, MD
Professor & Dean for Child Health Research
Gogel Family Chair & Director of The Mindich Child Health & Development Institute
Director of the Center for Molecular Cardiology
Departments of Pediatrics and Genetics & Genomic Sciences
Icahn School of Medicine @ Mount Sinai
presents, "The RASopathies: Too much, too little and getting to just right" Hosted by: Dr. Peter Jin In-person only: Connor Auditorium (FLTC)
Find out more »April 2023
Karen Oegema, PhD
Professor
Department of Cellular & Molecular Medicine
University of California, San Diego School of Medicine
presents, "Mitotic centrosomes: assembly & functions" Hosted by: Dr. Susan Dutched In-person only: Connor Auditorium (FLTC)
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Jennifer Wang, PhD
Assistant Professor
Department of Biology
Washington University in St. Louis
presents, "Fitting the pieces together: how cells make centrosomes and cilia" Hosted by: Dr. Tychele Turner In-person only: Connor Auditorium (FLTC)
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Ali Mortazavi, PhD
Professor
Department of Developmental and Cell Biology
University of California, Irvine
presents, "Title TBD" Hosted by: Dr. Heather Lawson In-person only: Connor Auditorium (FLTC)
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Ellen Hoffman, MD, PhD
Assistant Professor
Yale Child Study Center & Yale Neurogenetics Program
Yale University School of Medicine
presents, "Functional analysis of autism risk genes in zebrafish" Hosted by: Dr. Joe Dougherty In-person only: Connor Auditorium (FLTC)
Find out more »May 2023
Jesse Engreitz, PhD
Assistant Professor
Department of Genetics
Stanford University
presents, "Mapping the regulatory wiring of the genome to connect disease variants to functions" Hosted by: Dr. Heather Lawson In-person only: Connor Auditorium (FLTC)
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Lacra Bintu, PhD
Assistant Professor of Bioengineering
Department of Bioengineering
Stanford University
presents, "The sequence determinants of human transcriptional activators and repressors: high-throughput discovery and systematic perturbations" Hosted by: Dr. Barak Cohen In-person only: Connor Auditorium (FLTC)
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Kristopher Kahle, MD, PhD
Associate Professor & Director, Pediatric Neurosurgery
Department of Neurosurgery
Harvard Medical School and Massachusetts General Hospital
presents, "Genomics of developmental brain anomalies" Hosted by: Dr. Peter Jin In-person only: Connor Auditorium (FLTC)
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Ben Major, PhD
Alan A. and Edith L. Wolff Professor of Cell Biology and Physiology
Departments of Cell Biology & Physiology and Otolaryngology
Washington University School of Medicine
presents, "Protein-protein proximity networks reveal therapeutic vulnerabilities in cancer" Hosted by: Dr. Tychele Turner In-person only: Connor Auditorium (FLTC)
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