The Morris lab published a paper recently in Nature. The paper, “Single-cell mapping of lineage and identity in direct reprogramming,” shows that expression of a putative methyltransferase, Mettl7a1, is associated with the successful reprogramming trajectory; and adding Mettl7a1 to the reprogramming cocktail increases the yield of induced endoderm progenitors. Brent Biddy, a graduate student in the Morris lab, is first author on the paper.
Congratulations to all! Read more about the Morris lab here.