The Calling Cards team in the Department of Genetics at Washington University School of Medicine in St. Louis had their preprint on self-reporting transposons selected for a prelight. The prelight contains additional insights about the paper from Arnav Moudgil, a graduate student in Dr. Rob Mitra’s lab and first author on the paper, and Dr. Rob Mitra, Associate Professor in the Department of Genetics and the Alvin Goldfarb Distinguished Professor of Computational Biology. The preprint, “Self-reporting transposons enable simultaneous readout of gene expression and transcription factor binding in single cells,” shows recovery of cell type-specific BRD4 and SP1 binding sites from cultured cells and maps Brd4 binding sites in the mouse cortex at single cell resolution, establishing a new technique for studying TF biology in situ. Senior authors on the paper include Dr. Samantha Morris, Assistant Professor in the Department of Genetics at Washington University School of Medicine in St. Louis, Dr. Joe Dougherty, Associate Professor in the Department of Genetics, and Dr. Rob Mitra. Congratulations, all!
