Mayank Choudhary, a graduate student in the Wang Lab, had a paper published recently in Genome Biology. The paper, “Co-opted transposons help perpetuate conserved higher-order chromosomal structures,” shows that transposable elements heavily contribute to the formation of species-specific loops in humans and mice through deposition of novel anchoring motifs, and to the maintenance of conserved loops across both species through CTCF binding site turnover. Ryan Friedman, a graduate student in the Cohen Lab, Julia Wang, a graduate student in the Ding Lab, Xiaoyu Zhuo, a postdoc in the Wang Lab, Josh Jang, a graduate student in the Wang Lab, and Ting Wang, Ph.D., Professor of Genetics, Professor of Computer Science and Engineering, and the Sanford and Karen Loewentheil Distinguished Professor of Medicine at Washington University, are also authors.
