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Bruce Gelb, MD
Professor & Dean for Child Health Research
Gogel Family Chair & Director of The Mindich Child Health & Development Institute
Director of the Center for Molecular Cardiology
Departments of Pediatrics and Genetics & Genomic Sciences
Icahn School of Medicine @ Mount Sinai
March 30 @ 12:00 pm - 1:00 pm
presents, “The RASopathies: Too much, too little and getting to just right”
Talk abstract: Noonan syndrome and the related disorders, now called the RASopathies, are phenotypically related traits arising from perturbations, largely engendering gain of function, in the RAS/mitogen-activated protein kinase signal transduction pathway. In this lecture, insights gained from phenotype-first and genotype-first studies of the RAsopathies will be provided as well as those from cell and animal model research, informing the development of mechanistic therapies for these genetic traits.
Hosted by: Dr. Peter Jin
In-person only: Connor Auditorium (FLTC)