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October 2022

Emma Farley, PhD
Assistant Professor
Department of Medicine
University of California-San Diego

October 13 @ 12:00 pm - 1:00 pm

presents, "Affinity optimizing enhancer variants disrupt development" Hosted by: Dr. Barak Cohen In-person only:  Connor Auditorium (FLTC) Talk abstract:  An emerging regulatory principle governing enhancers is the use of suboptimal affinity binding sites to encode tissue-specific gene expression during development. Here we discover that affinity optimizing single-nucleotide variants can violate this principle, disrupt tissue-specific gene expression, and alter phenotypes in Ciona, mice, and humans.

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Barbara Cheifet, PhD
Senior Editor
Nature Biotechnology
Springer Nature

October 20 @ 12:00 pm - 1:00 pm

presents, "Publishing for impact" Hosted by: Dr. Ting Wang In-person only:  Connor Auditorium (FLTC) Talk abstract:  In this talk, I will share tips on the publishing process, what journals look for, and how to productively interact with editors. I will also look forward to answering any questions related to academic publishing.

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Laurence Pelletier, PhD
Principal Investigator & Cancer Cell Biologist
Lunenfeld-Tanenbaum Research Institute, Toronto

October 27 @ 12:00 pm - 1:00 pm

presents, "Protein interaction profiling of centrosomes in normal and disease states" Hosted by:  Dr. Susan Dutcher In-person only:  Connor Auditorium (FLTC)

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November 2022

Kun Zhang, PhD
Professor
Department of Bioengineering
University of California, San Diego

November 10 @ 12:00 pm - 1:00 pm

presents, "A multi-omics cell atlas for human healthy and disease kidney" Hosted by:  Dr. Shamim Mollah In-person only:  Connor Auditorium (FLTC) Talk abstract:  Detailed characterization of the cell types comprising the highly complex human organs is essential to understanding their functions. Such tasks require highly scalable experimental approaches to examine multiple aspects of the molecular state of individual cells, registering cells to 3D coordinates, as well as the computational integration to produce unified cell state annotations and interpretation with biological…

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Samantha Morris, PhD
Associate Professor
Departments of Genetics and Developmental Biology
Washington University School of Medicine

November 17 @ 12:00 pm - 1:00 pm

presents, "What are my cells? A journey into cell identity and new genomic technologies" Hosted by: Dr. Joe Dougherty In-person only:  Connor Auditorium (FLTC) Talk abstract:  A mechanistic understanding of how cell identity is established and maintained is fundamental to the precise engineering of cell fate. Here, I will present new genomic technologies developed by my lab to permit single-cell lineage tracing throughout reprogramming, accompanied by recording of TF-binding and chromatin accessibility profiling. Integrating this information using our unique computational tools for interrogating gene regulatory networks…

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December 2022

Hui Shen, PhD
Associate Professor
Department of Epigenetics
Van Andel Institute

December 1 @ 12:00 pm - 1:00 pm

presents, "Epigenetics’: Lesson Learned from Ovarian Cancer and the Female Reproductive Tract " Hosted by:  Dr. Ting Wang In-person only:  Connor Auditorium (FLTC)

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Student-invited speaker
Stephen Johnson Memorial Lecture
Jessica Tollkuhn, PhD
Associate Professor
Cold Spring Harbor Laboratory

December 8 @ 12:00 pm - 1:00 pm

presents, "Hormonal regulation of gene expression defines sex-variable biology" Hosted by:  Simona Sarafinovska and Genetics trainees & postdocs In-person only:  Connor Auditorium (FLTC)

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Jeffrey Miner, PhD
E & J Slatopolsky Professor of Medicine in Nephrology
Division of Nephrology
Department of Medicine
Washington University School of Medicine

December 15 @ 12:00 pm - 1:00 pm

presents, "Genetic manipulation of the kidney’s filtration barrier: insights into Alport syndrome" Hosted by:  Dr. Tychele Turner In-person only:  Connor Auditorium (FLTC)

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