BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Genetics//NONSGML Events//EN
CALSCALE:GREGORIAN
X-ORIGINAL-URL:https://genetics.wustl.edu/events/
X-WR-CALDESC:Genetics - Events
BEGIN:VEVENT
UID:20240513T1949Z-1715629742.8385-EO-3112-1@10.73.2.159
STATUS:CONFIRMED
DTSTAMP:20260414T030846Z
CREATED:20240513T174637Z
LAST-MODIFIED:20250404T172727Z
DTSTART;TZID=America/Chicago:20250410T120000
DTEND;TZID=America/Chicago:20250410T130000
SUMMARY: Genetics Seminar:  Ilhem Messaoudi\, PhD
DESCRIPTION: Ilhem Messaoudi\, PhD\, Professor and Chair\, University of Ke
 ntucky Presents:  Epigenetic remodeling of monocytes and macrophages by chr
 onic ethanol consumption Host:  Dr. Guoyan Zhao In person only:  Connor Aud
 itorium (FLTC) Abstract: In the United States\, 29.5 million people aged 12
  and above suffer from alcohol use disorder (AUD) and 61 million people eng
 age in binge drinking. Chronic […]
X-ALT-DESC;FMTTYPE=text/html: <h5>Ilhem Messaoudi\, PhD\, Professor and Cha
 ir\, University of Kentucky</h5><p>Presents:  <em>Epigenetic remodeling of 
 monocytes and macrophages by chronic ethanol consumption</em></p><p>Host:  
 Dr. Guoyan Zhao</p><p>In person only:  Connor Auditorium (FLTC)</p><p>Abstr
 act: In the United States\, 29.5 million people aged 12 and above suffer fr
 om alcohol use disorder (AUD) and 61 million people engage in binge drinkin
 g. Chronic alcohol consumption (CAC) is associated with significant increas
 ed morbidity and mortality\, predisposes individuals to serious infections\
 , and impairs wound healing. These observations indicate a dysregulation of
  the immune system by CAC. Many labs\, including ours\, have shown that CAC
  disproportionally impacts macrophages and monocytes. These cells play a cr
 itical role in antimicrobial defense and tissue homeostasis. Specifically\,
  CAC drives a hyper-inflammatory response by monocytes and macrophages. The
 se alcohol-induced exacerbated inflammatory responses are mediated by incre
 ased chromatin accessibility at promoters and intergenic regions that regul
 ate inflammatory responses.<img class="alignnone size-full wp-image-3881" s
 rc="https://genetics.wustl.edu/app/uploads/2024/05/1-20.png" alt="" width="
 1545" height="2000" /> <img class="alignnone size-full wp-image-3882" src="
 https://genetics.wustl.edu/app/uploads/2024/05/2-18.png" alt="" width="1545
 " height="2000" /></p>
CATEGORIES:Spring 2025
LOCATION:Connor Auditorium (FLTC)
GEO:0;0
ORGANIZER;CN="e.gan":MAILTO:e.gan@wustl.edu
URL;VALUE=URI:https://genetics.wustl.edu/events/event/genetics-seminar-27/
END:VEVENT
BEGIN:VTIMEZONE
TZID:America/Chicago
BEGIN:DAYLIGHT
TZOFFSETFROM:-0600
TZOFFSETTO:-0500
DTSTART:20250309T080000
TZNAME:CDT
END:DAYLIGHT
END:VTIMEZONE
END:VCALENDAR