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UID:20250312T2201Z-1741816896.0977-EO-3855-1@10.73.10.188
STATUS:CONFIRMED
DTSTAMP:20260424T142352Z
CREATED:20250312T213220Z
LAST-MODIFIED:20250312T223617Z
DTSTART;TZID=America/Chicago:20250318T140000
DTEND;TZID=America/Chicago:20250318T150000
SUMMARY: Genetics Special Seminar – Matthew Lorincz\, PhD
DESCRIPTION: Matthew Lorincz\, PhD\, Professor\, Department of Medical Gene
 tics University of British Columbia\, Vancouver Presents:  Chromatin-guided
  DNA methylation of CpG island promoters: insights from the early mouse emb
 ryo Host: Dr. Ting Wang In Person Only: Couch Building\, Conference Rm. 600
 1B Abstract: The vast majority of CpG island promoters remain hypomethylate
 d throughout development. However\, a subset of […]
X-ALT-DESC;FMTTYPE=text/html: <h3>Matthew Lorincz\, PhD\, Professor\, Depar
 tment of Medical Genetics University of British Columbia\, Vancouver</h3><p
 >Presents:  <em>Chromatin-guided DNA methylation of CpG island promoters: i
 nsights from the early mouse embryo</em></p><p>Host: Dr. Ting Wang</p><p>In
  Person Only: Couch Building\, Conference Rm. 6001B</p><p>Abstract: The vas
 t majority of CpG island promoters remain hypomethylated throughout develop
 ment. However\, a subset of such promoters are subject to de novo methylati
 on and transcriptional silencing in the early mouse embryo. I will present 
 unpublished work aimed at identifying the epigenetic features that promote 
 or protect these CpG-rich regions against DNA methylation at this developme
 ntal stage\, and compare these features to those required for de novo DNA m
 ethylation of CpG island promoters in the germline.</p><p><img class="align
 none size-full wp-image-3859" src="https://genetics.wustl.edu/app/uploads/2
 025/03/1.png" alt="" width="1545" height="2000" /> <img class="alignnone si
 ze-full wp-image-3860" src="https://genetics.wustl.edu/app/uploads/2025/03/
 2.png" alt="" width="1545" height="2000" /></p>
CATEGORIES:SPECIAL SEMINAR
LOCATION:Couch Bldg.\, Rm. 6001B
GEO:38.634194;-90.260875
ORGANIZER;CN="Michelle Gibbs":MAILTO:gibbsm@wustl.edu
URL;VALUE=URI:https://genetics.wustl.edu/events/event/genetics-special-semi
 nar-matthew-lorincz-phd/
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TZID:America/Chicago
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TZOFFSETFROM:-0600
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DTSTART:20250309T080000
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