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UID:20241210T1432Z-1733841150.1828-EO-3679-1@10.73.10.188
STATUS:CONFIRMED
DTSTAMP:20260417T200101Z
CREATED:20241210T142607Z
LAST-MODIFIED:20251006T201420Z
DTSTART;TZID=America/Chicago:20251016T120000
DTEND;TZID=America/Chicago:20251016T130000
SUMMARY: Genetics Seminar Series – Guangyong Peng\, MD\, PhD
DESCRIPTION: Guangyong Peng\, MD\, PhD Professor\, Department of Otolaryngo
 logy-Head and Neck Surgery WashU Medicine Talk Title: Senescent T Cells in 
 the Tumor Microenvironment: Emerging Challenges for Immunotherapy Host: Dr.
  Tristan Li Abstract: Current immunotherapies have obtained promising resul
 ts in cancer patients\, but the overall effectiveness rates still vary amon
 g the tumor types. One of the key determinants for […]
X-ALT-DESC;FMTTYPE=text/html: <h4>Guangyong Peng\, MD\, PhD</h4><p>Professo
 r\, Department of Otolaryngology-Head and Neck Surgery</p><p>WashU Medicine
 </p><p>Talk Title: <em>Senescent T Cells in the Tumor Microenvironment: Eme
 rging Challenges for Immunotherapy</em></p><p>Host: Dr. Tristan Li</p><p>Ab
 stract: Current immunotherapies have obtained promising results in cancer p
 atients\, but the overall effectiveness rates still vary among the tumor ty
 pes. One of the key determinants for the therapeutic efficacy and immune re
 sponses is the functional state of the transferred/preexisting T cells in t
 he tumor microenvironment (TME). This seminar will share the following info
 rmation:</p><p>1) Identified that immunosenescence is an important T cell d
 ysfunctional state in the TME in addition to exhaustion.</p><p>2) Introduce
  the functional role of senescent T cells in maintaining and amplifying imm
 une suppression in the TME for tumor immunotherapy resistance.</p><p>3) Und
 erstand the potential mechanisms responsible for the development of senesce
 nt T cells in the TME.</p><p>4) Develop novel strategies to prevent T cell 
 senescence for enhancing tumor immunity and immunotherapy.</p><p><img class
 ="alignnone wp-image-4416 size-full" src="https://genetics.wustl.edu/app/up
 loads/2024/12/1-5.png" alt="" width="1545" height="2000" /> <img class="ali
 gnnone wp-image-4417 size-full" src="https://genetics.wustl.edu/app/uploads
 /2024/12/2-4.png" alt="" width="1545" height="2000" /></p>
CATEGORIES:Fall 2025
LOCATION:Connor Auditorium
GEO:38.635470;-90.262723
ORGANIZER;CN="Michelle Gibbs":MAILTO:gibbsm@wustl.edu
URL;VALUE=URI:https://genetics.wustl.edu/events/event/guangyong-peng-md-phd
 /
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DTSTART:20250309T080000
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