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UID:20241210T1520Z-1733844002.4464-EO-3697-1@10.73.10.188
STATUS:CONFIRMED
DTSTAMP:20260417T200108Z
CREATED:20241210T143651Z
LAST-MODIFIED:20260326T175907Z
DTSTART;TZID=America/Chicago:20260416T120000
DTEND;TZID=America/Chicago:20260416T130000
SUMMARY: Genetics Seminar Series – Elizabeth Pollina\, PhD
DESCRIPTION: Elizabeth Pollina\, PhD Assistant Professor Dept. of Developme
 ntal Biology WashU Medicine Talk Title: Dynamic Genome Control Mechanisms i
 n Nervous System Longevity Abstract: A striking feature of the nervous syst
 em is its continual adaptation to environmental cues throughout life. Envir
 onmental stimuli trigger changes in neuronal activity that\, in turn\, indu
 ce transcriptional programs that drive adaptive modifications […]
X-ALT-DESC;FMTTYPE=text/html: <h4>Elizabeth Pollina\, PhD</h4><p>Assistant 
 Professor</p><p>Dept. of Developmental Biology</p><p>WashU Medicine</p><p>T
 alk Title: <em>Dynamic Genome Control Mechanisms in Nervous System Longevit
 y</em></p><p>Abstract: A striking feature of the nervous system is its cont
 inual adaptation to environmental cues throughout life. Environmental stimu
 li trigger changes in neuronal activity that\, in turn\, induce transcripti
 onal programs that drive adaptive modifications to neuronal circuits. Howev
 er\, during transcription\, DNA can be cut\, unwound\, the reannealed in a 
 process that has the potential to create mutations. How then do animals bal
 ance the necessity of activity for brain plasticity with the intrinsic risk
  it poses to the genetic code? Here\, I discuss our lab’s ongoing efforts t
 o uncover the molecular mechanisms that regulate stimulus-dependent transcr
 iption and DNA repair in the brain and the significance of these genome con
 trol mechanisms for cognitive aging and neurodegenerative disease.</p><p>Ho
 sts: Drs. Lijuan Feng and Gabor Egervari</p><p><img class="alignnone wp-ima
 ge-4858 size-full" src="https://genetics.wustl.edu/app/uploads/2024/12/1-27
 .png" alt="" width="1545" height="2000" /> <img class="alignnone wp-image-4
 859 size-full" src="https://genetics.wustl.edu/app/uploads/2024/12/2-26.png
 " alt="" width="1545" height="2000" /></p>
CATEGORIES:Spring 2026
LOCATION:Connor Auditorium
GEO:38.635470;-90.262723
ORGANIZER;CN="Michelle Gibbs":MAILTO:gibbsm@wustl.edu
URL;VALUE=URI:https://genetics.wustl.edu/events/event/pollina-elizabeth-202
 6/
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TZID:America/Chicago
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TZOFFSETFROM:-0600
TZOFFSETTO:-0500
DTSTART:20260308T080000
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