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UID:20241210T1432Z-1733841150.1685-EO-3677-1@10.73.10.188
STATUS:CONFIRMED
DTSTAMP:20260423T142206Z
CREATED:20241210T142454Z
LAST-MODIFIED:20250910T213524Z
DTSTART;TZID=America/Chicago:20251002T120000
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SUMMARY: Precision Medicine Pathway Keynote Address – Hal Dietz\, MD
DESCRIPTION: Hal Dietz\, MD Johns Hopkins University School of Medicine Hos
 ts: Tim Schedl\, PhD\, Emma Casey Title: Leveraging Nature’s Success: Lesso
 ns from Modifiers of Vascular Connective Tissue Disorders Abstract: We have
  identified the genes responsible for many syndromic presentations of aorti
 c and arterial fragility. Using animal models\, we have defined the pathoge
 nic sequence for loss of arterial wall homeostasis […]
X-ALT-DESC;FMTTYPE=text/html: <h4>Hal Dietz\, MD</h4><p>Johns Hopkins Unive
 rsity School of Medicine</p><p><strong>Hosts:</strong> Tim Schedl\, PhD\, E
 mma Casey</p><p><strong>Title: </strong><em>Leveraging Nature’s Success: </
 em><em>Lessons from Modifiers of Vascular Connective Tissue Disorders</em><
 /p><p><strong>Abstract:</strong> We have identified the genes responsible f
 or many syndromic presentations of aortic and arterial fragility. Using ani
 mal models\, we have defined the pathogenic sequence for loss of arterial w
 all homeostasis and\, in that manner\, have shown that targetable cellular 
 signaling events are the predominant drivers of vascular catastrophe. On th
 e basis of this work\, a variety of treatment strategies have been validate
 d and are in widespread clinical use for patients with these conditions.</p
 ><p><img class="alignnone wp-image-4371 size-full" src="https://genetics.wu
 stl.edu/app/uploads/2024/12/1-3.png" alt="" width="1545" height="2000" /></
 p><p><img class="alignnone wp-image-4358 size-full" src="https://genetics.w
 ustl.edu/app/uploads/2024/12/2-2.png" alt="" width="1545" height="2000" /><
 /p>
CATEGORIES:Fall 2025
LOCATION:Connor Auditorium
GEO:38.635470;-90.262723
ORGANIZER;CN="Michelle Gibbs":MAILTO:gibbsm@wustl.edu
URL;VALUE=URI:https://genetics.wustl.edu/events/event/precision-medicine-pa
 thway-keynote-address/
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