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UID:20241210T1520Z-1733844002.3735-EO-3707-1@10.73.10.188
STATUS:CONFIRMED
DTSTAMP:20260417T200106Z
CREATED:20241210T144547Z
LAST-MODIFIED:20260122T143949Z
DTSTART;TZID=America/Chicago:20260129T120000
DTEND;TZID=America/Chicago:20260129T130000
SUMMARY: Genetics Seminar Series – Gwendalyn J. Randolph\, PhD
DESCRIPTION: Gwendalyn J. Randolph\, PhD Emil R. Unanue Professor\, Departm
 ent of Pathology & Immunology WashU Medicine Host: Dr. Jim Skeath Talk Titl
 e: Peritoneal cavity macrophages in mouse and humans – differentiation\, he
 terogeneity\, and roles in disease Abstract: In this seminar\, I will descr
 ibe our work defining the heterogeneity of resident macrophages in the body
  cavity\, beginning […]
X-ALT-DESC;FMTTYPE=text/html: <h4>Gwendalyn J. Randolph\, PhD</h4><p>Emil R
 . Unanue Professor\, Department of Pathology & Immunology</p><p>WashU Medic
 ine</p><p>Host: Dr. Jim Skeath</p><p>Talk Title: <em>Peritoneal cavity macr
 ophages in mouse and humans – differentiation\, heterogeneity\, and roles i
 n disease</em></p><p>Abstract: In this seminar\, I will describe our work d
 efining the heterogeneity of resident macrophages in the body cavity\, begi
 nning with mouse and proceeding to work that compares mouse and human perit
 oneal macrophages\, taking into account the fluid and tissue compartments o
 f the unique peritoneal space that are both rich in macrophages. This resea
 rch involving single cell RNA profiing in both species\, profiling and gene
 tic manipulation in mice\, use of humanized mice and human samples\, identi
 fies key similarities and key differences between the two species. Findings
  will be discussed in relation to the possibility that the results might im
 pact approaches to peritoneal conditions as varied as peritoneal adhesions\
 , endometriosis\, peritoneal tumors and metastases\, and spread of infectio
 n in the cavity.</p><p><img class="alignnone wp-image-4622 size-full" src="
 https://genetics.wustl.edu/app/uploads/2024/12/1-16.png" alt="" width="1545
 " height="2000" /> <img class="alignnone wp-image-4623 size-full" src="http
 s://genetics.wustl.edu/app/uploads/2024/12/2-15.png" alt="" width="1545" he
 ight="2000" /></p>
CATEGORIES:Spring 2026
LOCATION:Holden Auditorium
GEO:38.636879;-90.262646
ORGANIZER;CN="Michelle Gibbs":MAILTO:gibbsm@wustl.edu
URL;VALUE=URI:https://genetics.wustl.edu/events/event/randolph-g-2026/
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TZID:America/Chicago
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DTSTART:20251102T070000
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