Researchers Illuminate the Epigenetic Basis of Microglial Plasticity

A collaborative research effort between the laboratories of Qingyun Li, PhD, assistant professor in the Departments of Genetics and Neuroscience, and Harrison Gabel, PhD, associate professor in the Department of Neuroscience at Washington University School of Medicine has uncovered fundamental mechanisms that govern how microglia—the brain’s resident immune cells—adapt their functional states across development, aging, and disease. The study, “State-specific enhancer landscapes govern microglial plasticity,” was recently published in Immunity.

Graduate student Kia Barclay receives Provost’s Research Excellence Award

Graduate student Kia Barclay of the Li Lab has been selected as a Graduate Student Recipient of the 2025 Provost’s Research Excellence Award, a prestigious university-wide honor recognizing outstanding research achievement. Barclay is one of only seven students across both the Danforth and Medical campuses to receive the award this year—and the sole honoree representing the School of Medicine, underscoring the exceptional impact of her scientific contributions.