From deciphering underlying genetic factors of diseases to developing cutting-edge genome technology, our scientists are making impactful discoveries everyday.
Strength in Genetics and Genomics Research
The Department of Genetics has traditional strengths in computational biology and genome science, as well as model organism, evolutionary and human genetics. Recent specialties include neurological disorders, cellular bioenergetics, epigenomics, personalized medicine and genome technology development.
We have established leadership in the following flagship NIH genomic medicine themed projects:
- The Human Pangenome Project (NHGRI)
- The Impact of Genetic Variation on Function (NHGRI)
- The Long Life Family Study (NIA)
- Somatic Mosaicism across Human Tissues (NIH Common Fund)
- Multi-Omics for Health and Disease (NHGRI, NCI, NIEHS)
- The BRAIN (The Brain Research through Advancing Innovative Neurotechnologies) Initiative Cell Atlas Network (NIMH)
Within the close-knit research community of Washington University School of Medicine, our scientists are supported by a strong foundation. School of Medicine Facts & Figures
| #2 NIH Funding (2024) | $683 Million Research Funding 2024 | 19 Nobel Laureates |
Latest News
Obituary: Guoyan Zhao, associate professor of genetics, neurology, 53 (Links to an external site)
Guoyan Zhao, an associate professor of genetics and of neurology at Washington University School of Medicine in St. Louis, died Friday, May 15, 2026. She was 53. Zhao was highly regarded for harnessing the tools of computational biology, genomic sequencing and single-cell analysis to shed light on neurological and neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease and chronic pain.
DNA damage can trigger neurons to self-destruct
WashU Medicine researchers identified key details in how DNA damage can flip a nerve cell’s self-destruct switch. The new study could lead to novel routes to preventing neurodegeneration in a variety of diseases.
Frederick “Eric” Arnold, PhD and Collaborators Receive Longitude Prize on ALS Discovery Award
Frederick “Eric” Arnold, PhD, an assistant professor of Genetics and collaborators from the University of Idaho have been selected to receive a £100,000 Discovery Award through the Longitude Prize on ALS, an international initiative focused on accelerating the discovery of new treatments for amyotrophic lateral sclerosis (ALS) using artificial intelligence.
