Joseph Dougherty, PhD

Joseph Dougherty, PhD

Professor of Genetics and Psychiatry

Dougherty Lab | Google Scholar Profile

Education & Training

  • Postdoctoral Training: Nathaniel Heintz, Rockefeller University, 2010
  • PhD: Neuroscience: University of California Los Angeles, 2005
  • BS: Truman State University, 1999

Major Awards

  • Highlighted as one of Genome Technology’s ‘Up and Coming Investigators’, 2012

Research Interests

I am broadly interested in how a single genome creates the cellular diversity that is discovered in the brain, and how perturbations of specific cell types in the brain may lead to disorders of the nervous system, as well as alterations of normal behavior. We approach these questions using the tools of mouse transgenics and conditional knockouts, but guide our studies using information gleaned from human genetics studies.

Key Publications

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Funded Research Projects

NIDA(Significant Contributor):Using Transgenic Mice to Examine the Role of CNIH3 Variants in Opioid Dependence
NIMH(PI):Regulation of Mammalian Social Behavior by the GTF2I Family of Proteins
NINDS(PI):Local Translation in Astrocytes
Simons Foundation(PI):4/4 SSC-ASC Whole Genome Sequencing Consortium: UTR mutation analysis
NINDS(Significant Contributor):Using Motor Neuron Specific miRNA to Understand and Develop Novel Therapeutics for Motor Neuron Disease
Brain and Behavior Research Foundation(PI):NARSAD Independent Investigator Grant
NHGRI(Significant Contributor):Massively Parallel Characterization of CIS-regulatory Elements in the Brain
Hope Center(Significant Contributor):Regulation of Stop Codon Readthrough of Aqp4 and Role in Aß Clearance
NIMH(PI):Highly Parallel Analysis of 5′ and 3′ UTR variants in Autism Spectrum Disorders

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