Alison Goate, DPhil,Jean C. & James W. Crystal Professor and Chair, Dept. of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai

Presents:  Human genetics implicates Efferocytosis as an Alzheimer’s disease risk hub

Host:  Dr. Peter Jin

In person only:  Connor Auditorium (FLTC)

Abstract: Integrative genomics has revealed that AD genetic risk alleles are enriched within microglial enhancers and pathway analyses have implicated efferocytosis as a disease risk hub. We are using induced pluripotent stem cells to model risk and reveal disease mechanism.