Recent Publications

Biophysical simulation enables segmentation and nervous system atlas mapping for image first spatial omicsAli, L. M., Yim, A. K. Y., Gerbi, E., Nguyen, T., Tu, N., Ikede, F., Sampaleanu, R., Grigore, D., Waligorski, J., Kremitzki, C., Yuan, L., Dong, W., Mitra, R., Milbrandt, J. & Buchser, W., Dec 2026, In: npj Systems Biology and Applications. […]

INSM1 governs a neuronal progenitor state that drives glioblastoma in a human stem cell modelDeSouza, P. A., Ishahak, M., Qu, X., McCornack, C., Annamalai, D., Mao, D. D., Vangipurapu, R., Fu, Y., Vessoni, A. T., Cleary, R. T., Han, R. H., Augsornworawat, P., Woodiwiss, T., Agovino, D., Sizemore, B., Kline, J., Borhani-Haghighi, M., Chen, H., […]

Finding Significant Hits in Networks: a network-based tool for analyzing gene-level P-values to identify significant genes missed by standard methodsAcharya, S., Moghaddam, V. A., Jung, W. J., Kang, Y. S., Liao, S., Province, M. A. & Brent, M. R., Mar 1 2026, In: Briefings in Bioinformatics. 27, 2, bbag061.Research output: Contribution to journal › Article […]

Acetate enhances long-term memory in female mice by sex-, context-, and brain region-specific epigenetic and transcriptional remodelingPeriandri, E. M., Dodson, K. M., De Luna Vitorino, F. N., Garcia, B., Glastad, K. M. & Egervari, G., Feb 24 2026, In: Science signaling. 19, 926, eaec0496.Research output: Contribution to journal › Article › peer-review

Ketogenic diet dampens excitatory neurotransmission by shrinking synaptic vesicle poolsStunault, M. I., Deng, P., Yadav, A., Periandri, E. M., de Luna Vitorino, F. N., Thomsen, M. B., Sponagel, J., Barfield, A. J., Ponce, R. J., Foroughi, L., Garcia, B., Egervari, G., Klyachko, V. A. & Ashrafi, G., Feb 24 2026, In: Cell Reports. 45, 2, […]

State-specific enhancer landscapes govern microglial plasticityHamagami, N., Kapadia, D., Barclay, K. M., Huang, Y., Abduljawad, N., Cheng, Z., McLaughlin, L., Singhania, D., Ding, X., Yang, J., Sun, Z., Karra, V., Du, S., Bayguinov, P., Yu, G., Li, Y. E., Gabel, H. W. & Li, Q., Feb 10 2026, In: Immunity. 59, 2, p. 288-305.e11Research output: […]

Time trends in the male to female ratio for autism incidence: population based, prospectively collected, birth cohort studyFyfe, C., Winell, H., Dougherty, J., Gutmann, D. H., Kolevzon, A., Marrus, N., Tedroff, K., Turner, T. N., Weiss, L. A., Yip, B. H. K., Yin, W. & Sandin, S., Feb 4 2026, In: BMJ. 392, e084164.Research output: […]

REV-ERB-alpha and -beta coordinately regulate astrocyte reactivity and proteostatic functionNadarajah, C. J., Li, M. Y., Quillin, E. I., Boyer, K., Dimitry, J. M., Chen, Y., King, M. W., Saliu, I. O., Lee, J., Sheehan, P. W., Davis, A. A., Lazar, M. A., Zhao, G. & Musiek, E. S., Feb 3 2026, In: Proceedings of the […]

Multiomic single nuclei profiling the mouse hippocampus reveals that ACSS2 confers neuronal resilience to tauopathyEgervari, G., Alexander, D. C., Huang, H., Donahue, G., Hogan, C., Mendoza, M., Xu, H., Lee, V., Garcia, B., Bonini, N. & Berger, S., Feb 2026, In: Alzheimer's and Dementia. 22, 2, e70998.Research output: Contribution to journal › Article › peer-review

RBFOX1 association with age at onset of Alzheimer's diseasethe Long-Life Family Study (LLFS), Estudio Familiar de Influencia Genetica en Alzheimer (EFIGA), and The National Institute on Aging Alzheimer's Disease Family Based Study (NIA-LOAD FBS), Feb 2026, In: Alzheimer's and Dementia. 22, 2, e71188.Research output: Contribution to journal › Article › peer-review

Distinct contributions of Etv2+ and Flk1+ progenitors to endothelial, hematopoietic, and cardiac lineagesAlleyne, D., Kim, M., Wu, J., Kwon, Y., Kim, Y. R., Kabir, A. U., Ishahak, M., Millman, J. R., Fan, C., Lee, H. J., Krchma, K., Xing, X., Lavine, K., Wang, T. & Choi, K., Jan 27 2026, In: Cell Reports. 45, 1, […]

An integrated view of the structure and function of the human 4D nucleomeDekker, J., Oksuz, B. A., Zhang, Y., Wang, Y., Minsk, M. K., Kuang, S., Yang, L., Gibcus, J. H., Krietenstein, N., Rando, O. J., Xu, J., Janssens, D. H., Henikoff, S., Kukalev, A., Andréa, W., Winick-Ng, W., Kempfer, R., Pombo, A., Yu, M. […]

Chronic Oxaliplatin Treatment Induces CIPN in Mice via Activation of the TXNIP PathwayDu, J., Sudlow, L. C., Shahverdi, K., Zhou, H., Yuede, C. M., Crock, L. W., Hunter, D. A., Golden, J., Mollah, S. A., Wood, M. D. & Berezin, M. Y., Jan 2026, In: Molecular Neurobiology. 63, 1, 92.Research output: Contribution to journal › […]

Whole blood transcriptional signatures of age and survival identified in long life family and integrative longevity omics studiesLi, M., Song, Z., Reed, E., Karagiannis, T. T., Andersen, S., Brent, M., Mateusiak, C., Acharya, S., Jung, W. J., Liao, S., Wojczynski, M. K., Feitosa, M. F., O’Connell, J. R., Montasser, M. E., Thorpe, R. J., Arbeev, […]

Unmasked: transposable elements as drivers and targets in cancerGrinwald, M. F., Saintilnord, W. N. & Wang, T., Jan 2026, In: Trends in Genetics. 42, 1, p. 30-45 16 p.Research output: Contribution to journal › Review article › peer-review

Genome-wide gene-sleep interaction study identifies novel lipid loci in 732,564 participantsNoordam, R., Wang, W., Nagarajan, P., Wang, H., Brown, M. R., Bentley, A. R., Hui, Q., Kraja, A. T., Morrison, J. L., O'Connel, J. R., Lee, S., Schwander, K., Bartz, T. M., de las Fuentes, L., Feitosa, M. F., Guo, X., Hanfei, X., Harris, S. […]

Approaches for identification of 5′ UTR mutations impacting translation and protein production from neurodevelopmental disorder genesPlassmeyer, S. P., Florian, C. P., Chase, R., Kasper, M. J., Mueller, S., Liu, Y., McFarland White, K., Sierra-Cortez, L., Fischer, A. D., Jungers, C. F., Djuranovic, S. P., Djuranovic, S. & Dougherty, J. D., Dec 15 2025, In: Cell […]

Investigating the neuronal role of the proteasomal ATPase subunit gene PSMC5 in neurodevelopmental proteasomopathiesKüry, S., Stanton, J. E., van Woerden, G. M., Bosc-Rosati, A., Hsieh, T. C., Bray, L., Oloudé, M., Rosenfelt, C., Scott-Boyer, M. P., Most, V., Wang, T., Papendorf, J. J., de Konink, C., Deb, W., Vignard, V., Studencka-Turski, M., Besnard, T., Hajdukowicz, […]

An optimized variant prioritization process for rare disease diagnostics: recommendations for Exomiser and GenomiserUndiagnosed Diseases Network, Cooperstein, I. B., Marwaha, S., Ward, A., Kobren, S. N., Carter, J. N., Guo, Z., Berger, Z. D., Manabe, Y., Jiang, Y. H., Karasozen, Y., Huang, Y., Timp, W., Halstead, W., Craigen, W. J., Byrd, W. E., Gahl, W. […]

Whole-genome sequencing reveals individual and cohort level insights into chromosome 9p syndromes9P-ARCH, Dec 2025, In: Genome medicine. 17, 1, 129.Research output: Contribution to journal › Article › peer-review