Frederick Arnold, PhD, Assistant Professor in the Department of Genetics at Washington University School of Medicine, has been awarded a 2025 Research Innovation Grant from the ALS Network and ALS United. The award provides $150,000 in funding over one year to support his research in amyotrophic lateral sclerosis (ALS).
Dr. Arnold’s project, “Investigating Hyperphosphorylation of Tau Serine 262 as a Novel Biomarker and Therapy Target in ALS,” will examine how specific modifications of the tau protein may function as biomarkers of disease progression and as potential targets for new therapeutic strategies. By advancing understanding of the molecular mechanisms underlying ALS, his work aims to inform improved diagnostic tools and identify new avenues for treatment.
The ALS Network Research Innovation Grants support bold, high-impact science with strong potential to accelerate progress against ALS — a progressive neurodegenerative disease that affects motor neurons in the brain and spinal cord. Recipients are selected through a competitive review process that evaluates both scientific excellence and the promise of meaningful impact for people living with ALS and their families.