Adam Wende, PhD,  Associate Professor, Departments – Molecular & Cellular Pathology, The University of Alabama at Birmingham

Presents: Metabolic signaling in transcriptional control of heart failure

Host: Dr. Peter Jin

In Person Only: Connor Auditorium

Abstract:  Cardiovascular diseases are the leading cause of death, and diabetes enhances susceptibility and severity of heart failure. Epidemiological studies support the hypothesis that poor glycemic control, even after corrected, impacts disease pathology. We will discuss evidence for glucose-mediated regulation of the transcriptional changes that are associated with pathological cardiac remodeling in this context.