Wenyi Wang, PhD, Professor, Dept. of Bioinformatics & Computational Biology, and Biostatistics, MD Anderson Cancer Center

Presents: Deciphering tumor heterogeneity for benefits from immunotherapy in cancer

Host:  Dr. Ting Wang

In person only:  Connor Auditorium (FLTC)

Abstract: In most cancers, the heterogeneity of cell composition within and between tumor samples is mirrored in complex variations at the molecular level. This molecular complexity includes both transcriptional variation (i.e., ecology) and genomic complexity (i.e., evolution) as tumors continually evolve and acquire new mutations. In this talk, I will tell two stories, one with genomic deconvolution and one with transcriptomic deconvolution, during which we have stumbled upon biological and clinical implications including benefits from immunotherapy.