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Researchers decode how a ketogenic diet modifies brain synaptic function

Researchers decode how a ketogenic diet modifies brain synaptic function
A collaborative research effort between laboratories at Washington University School of Medicine has identified molecular and cellular mechanisms by which a ketogenic diet (KD) alters synaptic communication in the brain — revealing how metabolic state can reshape neuronal networks at the transcriptional, epigenetic, and physiological levels. Spearheaded by first authors Marion Stunault, PhD, Pan-Yue Deng, PhD and Anjali Yadav, PhD, the study, “Ketogenic diet dampens excitatory neurotransmission by shrinking synaptic vesicle pools,” was recently published in Cell Reports and provides foundational insight into how diet-induced metabolic changes influence excitatory circuits in the hippocampus.

Zefan (Vivien) Li Named WashU Pivot 314 Fellow

Zefan (Vivien) Li Named WashU Pivot 314 Fellow
Zefan (Vivien) Li, a third-year graduate student in the Jin lab, has been selected for the 2026 cohort of Washington University in St. Louis’s Pivot 314 Fellowship, a competitive program that supports emerging leaders across disciplines.

Assistant Professor Aki Ushiki Awarded Preeclampsia Foundation’s Peter J. Pappas Research Grant

Assistant Professor Aki Ushiki Awarded Preeclampsia Foundation’s Peter J. Pappas Research Grant
Aki Ushiki, PhD, assistant professor in the Department of Genetics at Washington University School of Medicine in St. Louis, has been awarded a 2026 Peter J. Pappas Research Grant from the Preeclampsia Foundation. The award provides $99,997 in research funding to support innovative studies aimed at improving outcomes for pregnant individuals and babies affected by preeclampsia and related hypertensive disorders of pregnancy.

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