On Jan 26, 2024, two faculty members in the Department of Genetics were awarded a “Drum Major Award” by the 2024 Dr. Martin Luther King, Jr. Commemoration Planning Committee. Their contribution to the community is inspiring to each one of us.
Postdoc Profile: Ju Heon Maeng
Below we are going to delve into Ju Heon Maeng’s background, hobbies and research aspirations. What are you investigating? I am currently working on two projects. First, I am investigating transposable element-derived antigens in patient-derived glioblastoma stem cells upon epigenetic treatment. This project involves analyzing multi-omics data, including long-read CAGE data.Also, I’m studying transposable element […]
The Turner Lab Develops HAT to Call De Novo Variants for Short-read and Long-read Sequencing Data
The Turner Lab has recently released Hare And Tortoise (HAT), an automated de novo variant (DNV) detection workflow for highly accurate short-read and long-read sequencing data. The method was published in Bioinformatics in January 2024.
The Schedl Lab Receives R35 Grant
The Schedl Lab led by Dr. Tim Schedl recently received NIGMS R35 grant. The grant provides funding for studying “control of germline stem cells and the switch to meiotic development in C. elegans” for 5 years.
New computational tools developed to identify TE-derived antigens in cancer using long-read CAGE sequencing data
In the new study published in Genome Research, postdoctoral fellow Ju Heon Maeng has developed a suite of computational tools to significantly improve immunopeptidome detection from transposable element expression, utilizing long-read data.
Bioinformatics Pioneer Dr. Gary Stormo Retires
After 24 years of professorship at Washington University School of Medicine in St. Louis, Dr. Gary Stormo, the Joseph Erlanger Professor of Genetics, retires at the age of 73.
Dr. Yang (Eric) Li’s First-authored Paper Published in Nature
As part of NIH’s BRAIN Initiative, Nature recently published 10 papers mapping the first mammalian brain. Genetics Assistant Professor Dr. Yang (Eric) Li, a contributor in this project, co-first-authored one of the Nature papers titled: Single-cell analysis of chromatin accessibility in the adult mouse brain. Li has also contributed to two other papers in this […]
New Modbed Track Available on WashU Epigenome Browser
The WashU Epigenome Browser has introduced the Modbed track data type that allows for the visualization of modification details at the level of individual long reads, as well as the display of merged modification information for one or more long reads within a dynamic resolution range.
Collaborative Study Led by Graduate Student Reveals New Discoveries on Rare Disease
A new study led by WashU graduate student Shujuan Zhao, co-mentored by Dr. Sheng Chih (Peter) Jin, Assistant Professor of Genetics and Pediatrics, Washington University School of Medicine, and Dr. Kristopher T. Kahle, Director of Pediatric Neurosurgery, Massachusetts General Hospital, sheds light on new genetic mutations related to the disease and validations of the identified genes in mouse and zebrafish models. This collaborative work was recently published in Nature Communications.
Postdoc Profile: Tassia Mangetti Goncalves
Below we are going to delve into Tassia Mangetti Goncalves’ background, hobbies and research aspirations. What are you investigating? I’m working with mammalian whole genome-wide cis-regulatory modules. Cis-regulatory modules are regulatory regions in the genome. Spatiotemporal control of gene expression is of critical importance and appropriate gene expression depends on these regulatory elements. Also, mutations […]