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PI: Jeff Milbrandt, MD, PhD

Our laboratory studies the biological function of the GFL family of neurotrophic factors (GDNF, neurturin, persephin and artemin) that constitute the ligands for the Ret tyrosine kinase receptor, which is mutated in multiple endocrine neoplasia syndromes as well as thyroid cancers.

PI: Rob Mitra, PhD

The Mitra lab is interested in understanding how transcription factors achieve their in vivo specificities and dissecting the gene regulatory networks that govern developmental and disease processes. We are also interested in developing and applying methods for high throughput functional genomics.

PI: Samantha Morris, PhD

The Morris Lab is a stem cell and developmental biology laboratory. Our research focuses on dissecting and manipulating the gene regulatory networks that define cell identity, applying this knowledge to engineer clinically relevant cell types. We also develop new single-cell technologies to map cell lineage and identity in parallel to better understand how cell identity can be reprogrammed.

• Gabor Egervari, MD, PhD | Egervari Lab
• Peter Jin, PhD | Jin Lab
• Joe Dougherty, PhD | Dougherty Lab
• Jeffrey Milbrandt, MD, PhD | Milbrandt Lab
• Tychele Turner, PhD | Turner Lab
• Guoyan Zhao, PhD | Zhao Lab
• Tristan Qingyun Li, PhD | Li Lab
• Yang (Eric) Li, PhD | Li Lab

We invite highly motivated candidates to apply for positions as postdoctoral fellows in the laboratory of Dr. Jeff Milbrandt in the Department of Genetics at Washington University in St. Louis. Our primary goal is to unravel the mechanism of axon degeneration and its role in neurodegenerative disease. Many of our projects are pursued collaboratively with the Aaron DiAntonio lab and focus on how defects in NAD homeostasis alter disease progression in peripheral neuropathy, ALS and retinal degenerative disorders.

The laboratories of Dr. Jeff Milbrandt and Dr. Rob Mitra invite highly motivated candidates to apply for positions as joint postdoctoral fellows in the Department of Genetics and McDonnell Genome Institute at Washington University in St. Louis. These fellows will develop research programs in Personalized Medicine aimed at revealing the pathogenic mechanisms of disease-associated variants via monitoring phenotypic changes of genetically perturbed iPSC-derived neurons and glia.

Postdoctoral Research Associate position open in Dr. Guoyan Zhao’s laboratory (https://sites.wustl.edu/zhaolab/ ) in the Department of Genetics and Department of Neurology at Washington University School of Medicine. The Zhao laboratory employs multiple cutting-edge technologies in genomics and computational biology to investigate the development and function of mammalian brains in the context of human health and disease. Current areas of interest include applying single-nucleus RNA-sequencing and spatial transcriptomics/proteomics technologies on human brain with the goal of understanding disease pathogenesis of Alzheimer disease (AD), Parkinson disease (PD), and Lewy body diseases (LBDs).

We are currently seeking a postdoctoral fellow to lead research project (wet and/or dry) focused on abnormal pregnancy (pre-eclampsia) and/or craniofacial birth defects (craniofacial microsomia). The research involves analyzing GWAS variants using functional genomics and mouse genetics.

We’re looking for passionate, accomplished PhD scientists keen to take their research to the next level in one of the areas of our lab’s expertise. We offer competitive pay and benefits and a stimulating, collegial scientific environment optimal for academic, industry, or other career aspirations. Prospective postdocs should send Dr. Meers a CV with references, a brief explanation of their scientific/professional goals, and a description of how they envision a postdoc with our lab will help achieve them.

Postdoctoral Research Associate position is available immediately in the Departments of Genetics and Biochemistry & Molecular Biophysics at the Washington University in St. Louis. Multi-disciplinary research in the Egervari Lab focuses on the emerging area of metabolic-epigenetic interactions in the brain, particularly in the context of substance use disorders and neurodegeneration. We utilize cutting-edge proteomic, metabolomic and genomic approaches, including on the single cell level, to understand how metabolites influence chromatin and gene expression in the brain.